3M™ Polisher ST, BC25, EMP301STX080R, Luer, 2/Case
- 3M ID 70020346980
Details
Highlights
- Unaffected by process fluid turbidity up to 40 NTU
- The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification
- Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions
- Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution
- Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins
The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.
The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
Specifications
Resources
Connect with us. We’re here to help.
Pošljite nam sporočilo
Zahvaljujemo se vam za zanimanje za 3M. Da bomo na vaše vprašanje odgovorili v najkrajšem možnem času, vas vljudno prosimo, da navedete nekaj ključnih informacij, vključno z vašimi kontaktnimi podatki. Na osnovi posredovanih podatkov, bo na vaše vprašanje odgovoril po e-pošti ali telefonu predstavnik podjetja ali eden od naših pooblaščenih poslovnih partnerjev, s katerimi bomo morda delili vaše osebne podatke v skladu s politiko zasebnosti 3M.
Zahvaljujemo se vam, da ste se obrnili na podjetje 3M
Prejeli smo vaše sporočilo in zdaj obravnavamo vašo poizvedbo
Naš predstavnik vas bo kontaktiral po telefonu ali e-pošti.
An error occurred.
