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Zeta Plus™ Encapsulated System Scale-Up Filter Capsule, EXT, with ZB Series Media

3M ID 70020306885
  • Two layers of complementary porosities provide high contaminant holding capacity, economical filtration and reliable particle reduction
  • Highly charged resin provides negatively charged particle adsorption
  • FDA Drug Master File and USP Class VI Biological Reactivity Tests eases validation and regulatory submissions
  • Scaleable single use filter portfolio enables using the same filtration platform process liquids volumes of 0.5 to 20,000 liters
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Specifications
Attribute Name
Value
Brand
Zeta Plus™
Filter Material
Cellulose
Filter Type
Depth
Gasket/O-ring Material
Polysulfone
Grade
120ZB08A
Industries
Life Sciences
Product Series
Encapsulated
Series
Zeta Plus™ Encapsulated Series
Units per Case
1
Product Details
  • Two layers of complementary porosities provide high contaminant holding capacity, economical filtration and reliable particle reduction
  • Highly charged resin provides negatively charged particle adsorption
  • FDA Drug Master File and USP Class VI Biological Reactivity Tests eases validation and regulatory submissions
  • Scaleable single use filter portfolio enables using the same filtration platform process liquids volumes of 0.5 to 20,000 liters
  • Unique filter capsule design minimizes hold-up volume and maximizes product recovery, while reducing the need for cleaning validation; translucent plastic shell allows easy detection of the liquid level for real time monitoring of the filtration process and to minimize flush volumes
  • Cam-lock connections on 3M™ Zeta Plus™ Encapsulated capsules, and holder design allows for easy assembly and tear down of filtration system and improving productivity of manufacturing clean room

We developed the Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media to provide economical small scale clarification of pharmaceutical, biological, bioprocess, and cosmetic fluids. Our depth filtration media is composed of inorganic filter aid, cellulose and a positively charged resin system that pulls negatively charged contaminants from the fluid.

Our Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media are optimized for polishing clarification of mammalian cell harvest fluids and for protection of downstream sterilizing grade membrane filters. Their strong positive charge can provide more reduction of negatively charged contaminants than mechanical filtration alone. These products are manufactured to stringent quality controls that provide reproducible product performance from filter to filter, lot to lot. When used as a pre-filter, the high contaminant holding capacity of Zeta Plus Scale-Up Filter Capsules, EXT, with ZB Series Media can prolong the life of the final stage filter. Pharmaceutical Grade Media Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media are manufactured to controls described in our Drug Master File on record with the FDA. Certificates of Quality are included with every filter. These filters meet the requirements of USP Class VI Biological Reactivity Tests and meet the strict requirements specified in the Drug Master File, including product control and traceability. Encapsulating High Performance When faced with the challenges of filtration for the bioprocessing industry, where upstream cell culture clarification or downstream impurity removal is required, 3M™ Encapsulated Systems provide ergonomic, easy-to-use solutions. Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media are available in three sizes to meet varying volumes and applications and have been designed for minimal hold-up volume. They also incorporate 3 feet and rubber shoes for a firm, level posture on many surfaces and can also be stacked for convenience. Applications Parenterals, Dialysates Pharmaceuticals Antibiotics Growth Media Blood Fractionation Bioprocess Fluids, especially cell harvest polishing Cosmetic Applications We utilize the lenticular filter design and vertical flow path that has proven effective for depth filtration systems on our Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media. A total of four single-use scale-up devices are available for media grade selection and filter sizing. The BC25 capsule with 25 cm2 filter media is ideal for media grade screening. The Scale-Up Capsule filters with 170 cm2, 340 cm2 and 1020 cm2 media are designed for intermediate scale studies and low volume production filtration. Combined with the larger production scale capsules, the Zeta Plus Encapsulated System offers a completely single-use depth filter solution to process from 100ml to 25,000L of liquid.