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  6. 3M™ Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste, 12115, Vanilla Mint, 4 oz Tube

3M™ Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste, 12115, Vanilla Mint, 4 oz Tube

  • Part Number 12115
  • 3M Product Number 12115
  • 3M ID 7010387382
  • UPC 30348878312049

Strengthens teeth and repairs early lesions

Contains 1.1% NaF (5000 ppm fluoride ion) and an innovative calcium and phosphate ingredient

Proven remineralization throughout the lesion

View more details
Product Form Paste
Features Anti-cavity
Active Ingredient Sodium Fluoride
Fluoride Content 1.1 %
Flavor Vanilla Mint

Ways to purchase

  • dental patient
    Dental Patients

    Clinpro™ 5000 is a prescription toothpaste. To purchase, please contact your dentist directly to submit a prescription on your behalf.

    Already have Rx?

    If you already have a prescription, you can fill it at our participating online pharmacy, HealthWarehouse.

  • dental professional
    Dental Professionals

    For a complete list of distributors who sell authentic 3M dental products visit 3M Authorized Distributors.


  • Strengthens teeth and repairs early lesions
  • Contains 1.1% NaF (5000 ppm fluoride ion) and an innovative calcium and phosphate ingredient
  • Proven remineralization throughout the lesion
  • Creates acid-resistant mineral in dentin tubules*
  • Low abrasion even for exposed root surfaces
  • Replaces the patient’s current brushing regimen for easier compliance
  • Convenient 4oz tube
  • Offered in three great flavors: Vanilla Mint, Spearmint and Bubble Gum

3M™ Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste is a clinically proven prescription-strength formula containing functionalized tri-calcium phosphate (fTCP), an ingredient exclusive to 3M. This remineralizing toothpaste is used in a treatment plan for patients at high risk for caries to prevent and control tooth decay. Patients can use daily in place of conventional toothpaste.

Banner — Clinpro 5000: Tough on tooth decay. Easy on patients.

3M™ Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste, 12000 Series

Tough on tooth decay. Easy on patients.

  • Icon 2.1 — Clinpro 5000: Strengthens teeth
    Strengthens teeth

    An optimized pH results in enhanced remineralization. Clinpro 5000 provides remineralization throughout the whole lesion, not just on the surface.

  • Icon 2.2 — Clinpro 5000: One-step convenience
    One-step convenience

    This fluoride toothpaste replaces patients’ daily toothbrushing regimen, helping improve compliance. Its lowabrasion formula also makes it safe for exposed root surfaces.

  • Icon 2.3 — Clinpro 5000: 3M-exclusive technology
    3M-exclusive technology

    Featuring fTCP, an innovative ingredient exclusive to 3M, Clinpro 5000 Toothpaste releases fluoride, calcium and phosphate.

  • Icon 2.4 — Clinpro 5000: Clinically proven, prescription toothpaste
    Clinically-proven, prescription toothpaste

    Clinpro 5000 Toothpaste is backed by over 15 years of clinical usage and is proven to offer effective remineralization and help strengthen and repair enamel.

  • Image 3.1 — Clinpro 5000: A protective coating
    1. A protective coating around calcium and phosphate prevents early interactions with fluoride.

  • Image 3.2 — Clinpro 5000: During brushing, saliva breaks down the coating
    2. During brushing, saliva breaks down the coating.

  • Image 3.3 — Clinpro 5000: Calcium and phosphate are released
    3. Calcium and phosphate are released, making them available directly at the tooth surface along with fluoride.

Suggested applications
  • 3M™ Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste indicated for use as part of a professional program for the prevention and control of dental caries




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Frequently asked questions

Many patients are at an increased risk of getting tooth decay. For example, if you have had a recent filling, wear orthodontic braces, or use certain medicines that may cause dry mouth, you are at increased risk for cavities. Ask your dentist if you could benefit from using Clinpro 5000 toothpaste.
Clinpro 5000 is a prescription toothpaste containing, more than 4 times the fluoride found in over-the-counter toothpastes. This extra fluoride provides extra protection to the teeth.
The tri-calcium phosphate in Clinpro 5000 toothpaste is exclusive to 3M; it is coated to release calcium and phosphate when you brush your teeth. The calcium and phosphate in Clinpro 5000 toothpaste supplements the calcium and phosphate normally found in teeth and saliva to make sure it is available to react with the fluoride when and where you need it, at the tooth’s surface. The fluoride is attracted to the calcium and phosphate. All three ingredients come together to help build strong tooth mineral.
You should only use a pea-sized amount with each brushing. If used in this way, the tube should last about 6 months.
Clinpro 5000 toothpaste contains a higher level of fluoride than regular, over-the-counter toothpastes. This high level of fluoride makes Clinpro 5000 toothpaste a regulated medication that is only available by prescription. Many dentists dispense this product directly out of their office. If they prefer to write a prescription, it can be filled through a CVS pharmacy or, we suggest the online pharmacy HealthWarehouse.com. You will not find Clinpro 5000 toothpaste in the aisle of a grocery, drugstore or discount store.
Clinpro 5000 toothpaste is used once a day in place of your regular toothpaste to help prevent tooth decay. Discuss your level of risk for cavities with your dentist. Follow their recommendation on how long to continue using Clinpro 5000 toothpaste.
As with all sodium fluoride toothpastes, adults should avoid rinsing for 30 minutes after brushing with their teeth. This keeps the high level of fluoride on your teeth for the best results. Children between the ages of 6-16 years old should brush, spit, and rinse when using Clinpro 5000 toothpaste.
Please check with your dentist and doctor before using the product if you are pregnant.
If you have allergies to any of the product components, do not use this product. Use a thin ribbon or pea-sized amount of Clinpro 5000 toothpaste with each brushing. Swallowing too much Clinpro 5000 toothpaste may result in stomach pain, nausea, vomiting, and diarrhea. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Ask your dentist if Clinpro 5000 is right for you.
Please see prescribing information link above under Resources.