Promogran Matrix Family has been shown to be effective through multiple Randomized Controlled Trials (RCTs), that have been systematically reviewed in meta-analysis.(1)(2)
Promogran Prisma Matrix with ORC and Silver is cleared for use with 3M™ ActiV.A.C.™ Therapy System and its associated foam dressings: 3M™ V.A.C.® Granufoam™ Dressing and 3M™ V.A.C.® Simplace™ Dressing. These foam dressings can be used with either 3M™ V.A.C.® Drape or 3M™ Dermatac™ Drape.*
Studies have shown that the Promogran Matrix Family of collagen dressings:
Promogran Prisma Matrix is comprised of a sterile freeze-dried composite of 44% oxidized regenerated cellulose (ORC), 55% collagen and 1% silver-ORC with 25% w/w ionically bound silver, a well-known antimicrobial agent.
In the presence of exudate, Promogran Prisma Matrix transforms into a soft, confirmable, biodegradable gel, and thus allows contact with all areas of the wound. The dressing helps create a moist wound bed and an environment that supports wound healing.
During dressing changes it is not necessary to remove any residual dressing.
Note: When using Promogran Prisma Matrix in combination with ActiV.A.C. Therapy, any residual Promogran Prisma Matrix remaining in the wound should be removed before applying a new dressing.
*Please refer to
Instructions For Use for full application instructions.
1. Chowdhry S.A, et al. Use of oxidised regenerated cellulose/collagen dressings versus standard of care over multiple wound types: a systematic review and meta-analysis. Int Wound J. 2021. 2. Chen Y, Du P, Lv G. A meta-analysis examined the effect of oxidised regenerated cellulose/collagen dressing on the management of chronic skin wounds. Int Wound J. 2023;20(5):1544-1551. doi:10.1111/iwj.14009CHENET AL.1551 3. Snyder, R. et al. A Retrospective Study of Sequential Therapy with Advanced Wound Care Products versus Saline Gauze Dressings: Comparing Healing and Cost. Ostomy Wound Management. 2010; 56(11A):9–15. 4. Cullen B, et al. Early adoption of collagen/ORC therapies improves clinical outcome. Paper presented at: Wounds UK Harrogate, 2011. 5. Gottrup F, Cullen B, Karlsmark T, Bischoff-Mikkelsen M, Nisbet L, Gibson M. Randomized controlled trial on collagen/oxidized regenerated cellulose/silver treatment. Wound Repair & Regeneration. 2013; 21:1-10. 6. Veves A, Sheehan P, Pham HT. A randomised controlled trial of Promogran (a collagen/ oxidized regenerated cellulose dressing) vs standard treatment in the management of diabetic foot ulcers. Arch Surg. 2002; 137(7):822-827. 7. Vin, F., Teot, L. and Meaume, S. (2002) The healing properties of Promogran in venous leg ulcers. J Wound Care, 11, 335-341. 8. Bourdillon KA, Delury C, Cullen B. Biofilms and delayed healing – an in vitro evaluation of silver and iodine containing dressings and their effect on bacterial and human cells. International Wound Journal. 2017. ISSN 1742-4801.