3M™ Harvest RC

Products
  • Single-stage, single-use chromatographic clarification solution
  • Replaces primary, secondary, and guard membrane clarification stages
  • Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid
  • High mAb product recovery (>90-95%)
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Overall Diameter (Imperial)
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Overall Length (Imperial)
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Overall Width (Imperial)
Overall_Width_Imperial
Overall Height (Imperial)
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End Modification
End_Modification
Products Available
Available options:
 Overall Diameter (Imperial), Overall Length (Imperial), Overall Width (Imperial), Overall Height (Imperial) and End Modification
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Specifications
Attribute Name
Value
Application
Biopharmaceutical Manufacturing, Bioprocessing, Cell Culture Clarification, DNA Reduction, Fiber Chromatography, mAb Production, Single Stage Clarification, Turbidity Reduction
Autoclavable
No
Brand
3M™
Capsule Material
Fluorocarbon, Glass Filled Polypropylene, Polycarbonate, Polypropylene, Polysulfone, Silicone, Thermoplastic Elastomer
Effective Filtration Area (Metric)
0.23 m², 1.61 m², 1020 cm², 2.3 cm², 25 cm², 3.2 cm², 340 cm²
End Modification
1-1/2" Sanitary, 3/4" Sanitary, Luer-Lok
Filter Material
Functional Non-woven
Filter Technology
Anion exchange chromatography
Filter Type
Single Use
Gamma Compatible
No
Gamma Sterilized
No
Gasket/O-ring Material
Fluorocarbon, Silicone
Industries
Life Sciences
Inlet/Outlet Connections
1 1/2 in Sanitary Connectors, 3/4 in Sanitary Connectors, Luer Loc
Inlet Outlet Size
1.5", 3/4"
Maximum Capacity (Metric)
10 L, 15 mL, 160 L, 23 L, 250 mL, 3.4 L, 32 mL
Maximum Operating Pressure (Imperial)
40 psig, 45 psig, 50 psig
Maximum Operating Pressure (Metric)
2.8 bar, 3.1 bar, 3.4 bar
Maximum Operating Temperature (Celsius)
40 Degree Celsius
Maximum Operating Temperature (Fahrenheit)
104 Degree Fahrenheit
Membrane Type
PES
Micron Rating
0.2 μm
Minimum Capacity (Metric)
100 L, 14 L, 150 mL, 2 L, 20 mL, 6 L
Net Weight (Metric)
1.1 kg, 1.6 kg, 14.3 g, 3.4 kg, 69.2 g, 75.8 g, 9.8 kg
Overall Diameter (Imperial)
1.2 in, 1.7 in, 17.8 in, 3 in, 9.5 in
Overall Diameter (Metric)
2.9 cm, 24.1 cm, 4.3 cm, 45.2 cm, 7.7 cm
Overall Height (Imperial)
2.1 in, 2.2 in, 2.3 in, 2.4 in, 3.4 in, 3.5 in, 4.1 in, 6 in, 8 in
Overall Height (Metric)
10.4 cm, 15.2 cm, 20.3 cm, 5.3 cm, 5.7 cm, 5.9 cm, 6.1 cm, 8.6 cm, 8.8 cm
Overall Length (Imperial)
5 in
Overall Length (Metric)
12.8 cm
Overall Width (Imperial)
3.4 in
Overall Width (Metric)
8.5 cm
Saleable Unit
EA
Storage Temperature
32 °F - 86 °F
Storage Temperature (Celsius)
0 °C - 30 °C
Temperature Range (Celsius)
0 °C - 40 °C
Temperature Range (Fahrenheit)
32 °F - 104 °F
Units per Case
1, 12, 2, 4
Product Details
  • Single-stage, single-use chromatographic clarification solution
  • Replaces primary, secondary, and guard membrane clarification stages
  • Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid
  • High mAb product recovery (>90-95%)
  • Predictably scales from laboratory to manufacturing

3M™ Harvest RC is the next generation in harvest and clarification technology for high cell density cultures. This solution is designed as an efficient option to increase monoclonal antibody (mAb) yields while simplifying the upstream process by replacing the centrifuge and/or depth filtration unit operations.

Suggested Applications

  • Clarification for CHO harvest cell culture fluid
  • Significant turbidity reduction
  • Single-stage chromatographic clarification

Legal Disclaimer

Always follow your user instruction manual.