3M™ Single Bond Universal Adhesive Vial Refill

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Bonds dental restorations with uncompromising strength with a one-step, one-coat application.

Compatible with all etching techniques.

Compatible with all resin cements.

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Tech Data Sheet (PDF, 3MB)Safety Data Sheet (PDF, 0B)


  • Bonds dental restorations with uncompromising strength with a one-step, one-coat application
  • Compatible with all etching techniques
  • Compatible with all resin cements
  • Self- and dual-cure compatible with 3M™ Single Bond Universal DCA Dual-Cure Activator
  • Confidently bonds to both moist and dry dentin
  • Offers a strong bond to all indirect surfaces without an additional primer for more streamlined workflows
  • Results in virtually no post-operative sensitivity,* creating a better patient experience. *3M Internal data
  • Available in a flip-top vial for one-handed operation or unit dose delivery

Engineered for all etching techniques and all dental surfaces in your direct and indirect dental restorations, 3M™ Single Bond Universal Adhesive is the most clinically proven and peer-reviewed universal dental adhesive. Our convenient one-bottle adhesive doesn’t require an extra primer, offering you reliable bonding with one step and one coat — without compromising strength.

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Total versatility.
Uncompromising performance.

Designed for uncompromising bond strength with fewer steps, 3M™ Single Bond Universal Adhesive bonds to all dental surfaces, including enamel, dentin, glass ceramic, zirconia, noble and non-precious alloys and composites with no primer needed. In combination with 3M™ Single Bond Universal DCA Dual Cure Activator, Single Bond Universal Adhesive is compatible with all resin cements, core buildup materials and even self-cure composites. Our unique formulation optimizes the ratios of the 3M™ Vitrebond™ copolymer, HEMA and water. This results in reduced dental restoration technique sensitivity, consistent dental bonding and virtually no post-operative sensitivity in self-etch, selective-etch and total-etch applications.

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    Total versatility

    Compatible with all dental surfaces, direct and indirect applications and all etching techniques.

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    Confident bond strength

    Adhesive provides excellent bond strength on both moist and dry surfaces.

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    Convenient and hygienic delivery

    Available in flip-top vial for one-handed operation and unit-dose delivery.

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    Virtually no post-operative sensitivity*

    An evaluation of procedures from 120 dentists using different techniques found sensitivity rates of 0.4% for total-etch, 0.0% for selective-etch, and 0.06% for self-etch.*

    *3M internal data

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    Choose an adhesive backed by five years of clinical proof.

    There’s nothing like clinical proof to give you confidence when choosing dental products. This clinical evaluation documents the performance of 3M™ Single Bond Universal Adhesive over a five-year period. The study evaluated several variables important when choosing a dental adhesive. The results show that Single Bond Universal Adhesive is a truly versatile dental adhesive with excellent clinical performance regardless of technique.

Suggested applications
  • All classes of fillings with light-curing composite or compomer filling materials
  • Sealing of cavities and preparation of tooth stumps prior to temporary cementation of indirect restorations
  • Bonding of fissure sealants
  • Protective varnish for glass ionomer fillings
  • Cementation of indirect restorations when combined with RelyX Ultimate Adhesive Resin Cement
  • Cementation of veneers when combined with RelyX Veneer Cement
  • Bonding of core build-ups made of light-curing composite or core build-up materials
  • Bonding of dual-cure cements and core build-up materials and self-cure composites when combined with Single Bond Universal DCA
  • Repair of composite or compomer fillings
  • Intraoral repair of composite restorations, porcelain fused to metal, and all-ceramic restorations without extra primer
  • Root surface desensitization
  • Sealing of cavities prior to cementation of amalgam restorations