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  6. 3M™ Zeta Plus™ BC Series Filter Capsule with DEL Series Media

3M™ Zeta Plus™ BC Series Filter Capsule with DEL Series Media

Products
  • May help reduce undesirable lipids, lipoprotein haze, and microbial and particulate contaminants
  • Full range of cartridge and capsule filter sizes to enable laboratory to full-scale production operation
  • All product components comply with USP <88> Class VI Biological Reactivity Tests, in vivo
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Reduction Claims
Reduction_Claims
Overall Diameter (Imperial)
Overall_Diameter_Imperial
Overall Width (Imperial)
Overall_Width_Imperial
End Modification
End_Modification
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Available options:
 Reduction Claims, Overall Diameter (Imperial), Overall Width (Imperial) and End Modification
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Specifications
Attribute Name
Value
Application
Adsorptive Depth Filtration, Microbial Reduction Filtration
Brand
Zeta Plus™
Component and Assembly Materials
Cellulose
Effective Filtration Area
25 cm², 3.9 in²
Effective Filtration Area (Metric)
25 cm²
End Modification
Luer, Sanitary Fitting
Filter Material
Cellulose, Polypropylene
Filter Technology
Adsorbent
Filter Type
Depth
Flow Rate (Imperial)
25 GPM
Gasket/O-ring Material
N/A
Grade
DELI, DELP, DELP08A
Industries
Industrial, Life Sciences
Maximum Operating Temperature (Celsius)
40 Degree Celsius
Maximum Operating Temperature (Fahrenheit)
104 Degree Fahrenheit
Overall Diameter (Imperial)
2.63 in
Overall Diameter (Metric)
66.8 mm
Overall Width (Imperial)
9.84 in
Overall Width (Metric)
25 cm
Pressure Range
40 psig
Pressure Range (Metric)
2.8 bar
Reduction Claims
Lipid
Series
Zeta Plus™ BC Series, Zeta Plus™ DEL Series
Units per Case
4
Product Details
  • May help reduce undesirable lipids, lipoprotein haze, and microbial and particulate contaminants
  • Full range of cartridge and capsule filter sizes to enable laboratory to full-scale production operation
  • All product components comply with USP <88> Class VI Biological Reactivity Tests, in vivo

Our Zeta Plus™ BC Series Filter Capsule with DELP08 Series Media utilizes precipitated silica adsorbents that help reduce lipids, surfactants and, potentially, other biological contaminants from human blood plasma, serum-based products, recombinant proteins and other biological fluids. These two media types provide a range of lipid reduction capacity.

Problem:
During protein purification processes, lipid contamination can cause an assortment of processing problems. Lipids can foul and plug expensive chromatography columns and membrane filters. Lipid contamination can also cause solution instability of intermediate and final protein products leading haze.

Solution:
Our Zeta Plus™ BC Series filter capsules with DELP08 media may be an option to replace bulk precipitated silica operations, which are labor-intensive and require multiple operations to implement. Zeta Plus DEL08 series media can be used to help remove the following lipid classes: mono-, di-, and triglycerides, fatty acids, cholesterol, phospholipids, and lipoproteins. Reduction of lipid contaminants from protein solutions may lead to improved processing economies (e.g., extended column and membrane life), improved product purity, and increased final protein product stability. We manufacture Zeta Plus BC Series Filter Capsules using fluid contact components are compliant to USP <88> Class VI Biological Reactivity Tests.

Zeta Plus™ BC Series filter capsules with DELP08 media contains a mixture of precipitated silica aids, cellulose and a crosslinking polymer binder resin. The precipitated silica adsorbents provide the active component for lipid reduction. In addition, the polymer binding resin used in this product family contains a balance of tertiary and quaternary amines resulting in a positively charged media. The surface charge enhances the filtration effectiveness by attracting negatively charged contaminants too small for removal by mechanical sieving.