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How to Use-PDF (PDF, 142 KB)

How to Use-Video

Nasal Antiseptic Efficacy: A Summary of Clinical Evidence (PDF, 546 KB)

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Increase confidence in your nasal decolonization protocol.

  • 3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution 5% w/w [0.5% available iodine] USP) Patient Preoperative Skin Preparation was designed to help reduce the risk of factors that can lead to SSIs. With this product you can make a change that makes a real difference.

The effectiveness of 3M™ Skin and Nasal Antiseptic is backed by data from 10 investigator-initiated clinical studies.

  • swab icon

    Improves patient safety and protocol compliance without antibiotics.²

  • Zero infection icon

    Zero S. aureus infection in per protocol analysis with 3M Skin and Nasal Antiseptic, compared to mupirocin.²

  • icon representing film forming polymer

    Unique film-forming polymer increases persistence.

One simple step can help prevent SSIs.

  • 30% of surgical patients are already colonized with Staphylococcus aureus3

    30% of surgical patients are already colonized with S.aureus

  • 80% of SSIs from S.aureus come from the patient's own nasal flora4-6

    80% of SSIs from S.aureus come from the patient's own nasal flora.⁴⁻⁶

  • A single SSI can cost up to $60k per patient.7

    A single SSI can cost up to $60k per patient.⁷


Proven efficacy with a simple, one-time nasal antiseptic application.
  • 99.5% reduction in s. aureus in one hour graphic

    Providers can take control of preoperative nasal decolonization with 3M™ Skin and Nasal Antiseptic.

    Key benefits:
     

    • A simple, one-time application
    • Reduces nasal bacteria, including S. aureus by 99.5%, in just one hour
    • Maintains reduction for up to 12 hours⁸
    • SAFE for repetitive use

    As part of a comprehensive preoperative protocol, 3M™ Skin and Nasal Antiseptic is an important tool to help reduce SSIs while supporting antibiotic stewardship.²’⁹⁻¹²


  • Whitepaper icon

    Supporting Antibiotic Stewardship Through Effective Nasal Decolonization.

    This white paper provides examples of the clinical evidence and findings on 3M™ Skin and Nasal Antiseptic that demonstrate its efficacy, cost effectiveness and overall performance.

    Download the 3M™ Skin and Nasal Antiseptic White Paper


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  • 3M™ Skin and Nasal Antiseptic Clinical Evidence

    Evidence-based nasal decolonization supported by data. Lots of data.

    3M™ Skin and Nasal Antiseptic is the only nasal antiseptic supported by 10 investigator initiated studies. Download a summary of clinical evidence to learn how 3M™ Skin and Nasal Antiseptic is different from other solutions. Inside these summaries you’ll clearly learn that not all nasal antiseptics are created equally.

    Download 3M™ Skin and Nasal Antiseptic Clinical Evidence


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  • 3M™ Skin and Nasal Antiseptic

    Nasal Antiseptic Sample Request

    3M™ Skin and Nasal Antiseptic works with a quick one-time application prior to surgery and easily fits into the preoperative protocol, so compliance is ensured.

    3M™ Skin and Nasal Antiseptic Sample Request


  • 3M™ Skin and Nasal Antiseptic product brochure
    3M™ Skin and Nasal Antiseptic Product Brochure

    Learn more about what makes 3M™ Skin and Nasal Antiseptic a great addition to your pre-op protocol for nasal decolonization.

  • 3M™ Skin and Nasal Antiseptic Safety and Efficacy brochure
    3M™ Skin and Nasal Antiseptic Safety and Efficacy Brochure

    Read and review relevant info about a safety assessment of povidone-iodine and an overview of efficacy data.

  • facts about iodone
    Facts About Iodine and Iodophors

    Understand the truth about iodine sensitivities.

  • 3M™ Skin and Nasal Antiseptic Infographic
    3M™ Skin and Nasal Antiseptic Infographic

    Learn how to protect every patient, every time.


Want to learn more or request samples? Connect with a specialist.

References

  • 1. 3M Study-05-011017.

    2. Phillips M, Rosenberg A, Shopsin B, et al. Preventing surgical site infections: A randomized, open-label trial of nasal mup. ointment and nasal povidone-iodine solution. Infect Control Hosp Epidemiol. 2014;35:826-32

    3. Kuehnert MJ, Kruszon-Moran D, Hill HA, et al. Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001–2002. J Infect Dis. 2006;193:172-179.

    4. Perl TM, Cullen JJ, Wenzel RP, et al. Intranasal mup. to prevent postoperative Staphylococcus aureus infections. N Engl J Med. 2002;346:1871-1877.

    5. Kalmeijer MD, van Nieuwland-Bollen E, Bogaers-Hofman D, deBaere GAJ, Kluytmans JAJW. Nasal carriage of Staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery. Infect Control Hosp Epidemiol. 2000;21:319-323.

    6. Kluytmans JAJW, Mouton JW, Ijzerman EPF, et al. Nasal carriage of Staphylococcus aureus as a major risk factor for wound infections after cardiac surgery. J Infect Dis. 1995;171:216-219.

    7. Anderson DJ, Kaye KS, Chen LF, et al. Clinical and financial outcomes due to methicillin resistant Staphylococcus aureus surgical site infection: a multi-center matched outcomes study. PLoS ONE. 2009;4:e8305.

    8. 3M Study-05-011100.

    9. Bebko SP, Green DM, Awad SS. Effect of a preoperative decontamination protocol on surgical site infections in patients undergoing elective orthopedic surgery with hardware implantation. JAMA Surg.15;150:390-295.

    10. Brown L, Shelly M, Greene L, et al. The effect of universal intranasal povidone iodine antisepsis on total joint replacement surgical site infections. Presented at the APIC National Conference, Anaheim, CA, June 2014.

    11. Waibel ML. Revisiting process improvement for total joint arthroplasty SSI. Presented at the APIC National Conference, Fort Lauderdale, FL, June 2013.

    12. Hogenmiller JR, Hamilton J, Clayman T, et al. Preventing orthopedic total joint replacement SSIs through a comprehensive best practice bundle/checklist. Presented at the APIC National Conference, Baltimore, MD, June 2011.