V.A.C.® Therapy device on dark background

There is only one  3M™ V.A.C.® Therapy,  the original NPWT.

A world leader in negative pressure wound therapy - driven by science.

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V.A.C.® Therapy

V.A.C.® Therapy repeatedly sets the standard for negative pressure wound therapy (NPWT). Since it has been used to treat more than 10 million wounds¹ worldwide, there is reliable clinical evidence that associates V.A.C.® Therapy with reduced risk of readmission and reduced need of reoperation² — ultimately reducing hospitalization time and the risk of complications,³ Not all NPWT is the same, and choosing V.A.C.® Therapy can help improve patient care and your bottom line.

  •  circular blue icon with white outline showing half a fraction and half a clock face to represent half time savings
    1/2 the time for acute wounds and 1/3 the time for chronic wounds

    When V.A.C.® Therapy was initiated early in the wound care clinic treatment time period compared to late initiation, the days to reach significant closure (75% wound surface area reduction) were significantly decreased.⁴ Early initiation* of V.A.C.® Therapy has been shown to reduce 50% time for acute wounds and 65% time for chronic wounds.

    Based on a retrospective analysis conducted on a national insurance provider’s medical claims data, which examined 6,181 acute and 1,480 chronic wound patients that received NPWT from January 1, 2009 to June 30, 2011.
     

    *Defined as treatment within the first 7 days for acute wounds and 30 days for chronic wounds from the first wound treatment date.

  • V.A.C. lower total costs icon
    21%–34% lower total costs across wound types at 12 months

    In a retrospective analysis of U.S. insurance claims in the outpatient setting, patients who received V.A.C.® Therapy had lower total and wound-related treatment costs than patients who received competitor negative pressure wound therapy, in all wound types across all time periods studied.³

    See additional findings from this study (PDF, 640 KB)

  • Proven therapy icon
    Proven NPWT

    V.A.C.® Therapy continues to have the largest body of NPWT evidence in the world with 2,000+ peer-reviewed publications and more than 75% of published NPWT clinical evidence is based on V.A.C.® Therapy.⁵

    These studies have demonstrated several benefits of NPWT, as well as the effectiveness of V.A.C.® Therapy in helping to manage diabetic foot wounds, chronic wounds (e.g., pressure ulcers and lower extremity ulcers), and a variety of acute wounds.

Negative Pressure Wound Therapy products that can help you continue to strive for better outcomes

NOTE: Specific indications, contraindications, warnings, precautions, and safety information exist for these products and therapies. Please consult a clinician and product Instructions for Use prior to application. This material is intended for healthcare professionals. Rx only.

How does V.A.C.® Therapy work?

See the V.A.C.® Therapy Mechanism of Action

V.A.C.® Therapy is the original, foundational NPWT and one of the world leaders in NPWT. It promotes an environment for wound healing by protecting the wound from external contamination, providing a moist wound environment, and promoting the formation of granulation tissue.⁶

The combination of 3M’s proprietary foam, drape, multi-lumen tubing, and advanced algorithms enable you to provide a uniform negative pressure to the wound surface. This consistent negative pressure helps draw wound edges together, allows for the removal of exudate and infectious material, and stimulates the growth of tissue so the wound can heal.

Graphic image illustrating the mode of action for V.A.C.® Therapy on a wound
  • 1) Draws wound edges together

    The application of uniform negative pressure induces a physical response — macrostrain — that can be seen immediately as the wound edges are drawn together, allowing for optimal contact between the wound bed and the dressing.⁷

  • 2) Removes exudate and infectious material

    Macrostrain facilitates removal of wound exudate which may contain inhibitors of wound healing.⁶

  • 3) Reduces edema and promotes perfusion

    Removal of wound fluids assists in the reduction of edema, which facilitates the flow of blood into the wound bed, providing the oxygen and nutrients that are needed for wound healing.⁶

  • 4) Promotes granulation tissue formation

    In vitro/in vivo studies show that foam contact with tissue creates micro-deformation that leads to cell stretch.⁷ Cell stretch under negative pressure stimulates cellular activity that results in granulation tissue formation.⁸

    Over subsequent dressing changes, the granulation tissue fills the wound bed, further reducing the volume, and preparing it for final closure.

Learn what sets V.A.C.® Therapy apart

At 3M we focus on providing better healthcare solutions through science — designing around patients and those who care for them.

As a result of this commitment, bench testing in a simulated wound model with V.A.C.® Therapy versus other leading NPWT systems showed:
 

  • 90% more accurate delivery of negative pressure9
  • Removal of fluid 98% faster10
  • Removal of the same volume of fluid in 15 minutes that required 24 hours in other systems10
  • This is the first-ever acrylic and silicone hybrid drape for use with V.A.C.® Therapy. The forgiving silicone intelligently contours to the patient's body and allows for drape repositioning upon initial placement, while the high-tack acrylic layer provides a tight seal.

    Evidence shows it increases patient comfort: 100% (n=17) of patients in a customer preference test agreed that Dermatac Drape was painless upon removal.¹¹

    Explore Dermatac Drape

  • V.A.C.® Therapy is the only NPWT that features proprietary SensaT.R.A.C. Technology.
    In conjunction with specialized software, V.A.C.® Therapy detects blockages, senses pressure changes, and notifies you with alarms when target pressure is not achieved.

    Learn more about the SensaT.R.A.C. Technology (PDF, 2.2 MB)

    Explore SensaT.R.A.C. Technology

  • When granulation tissue formation is a key part of your patient’s healing, choose V.A.C.® Granufoam™ Dressings. These wound dressings come in multiple shapes and sizes to accommodate diverse wounds, and you can easily trim them to fit the contours of deep or irregularly shaped wounds.

    For patients with multiple wounds, you can customize the dressings for bridging techniques.

    Explore V.A.C.® Therapy dressings

Case study excerpt: Veraflo Therapy with V.A.C. Veraflo Cleanse Choice Dressing - chronic wound

A 61-year-old female underwent a complex right forefoot reconstruction due to a deformity. Both wound sites, the dorsal and medial incisions, developed a dermal dehiscence and were managed with serial debridements and 3M™ Silvercel™ Antimicrobial Alginate Dressing. The dorsal incision healed, but the medial incision demarcated and increased in depth.

The wound was mostly fibrinous with a small area of exposed bone. V.A.C.® Therapy was applied at -125mmHg, using a foam dressing and Dermatac Drape. After five days, the wound was mostly granular, with a small area of exposed bone. After the dressing change, V.A.C.® Therapy was discontinued due to the small size of the wound.

  • Image demonstrating V.A.C.® Therapy using Dermatac Drape from 0 to 9 days

    A) Application of 3M™ V.A.C.® Therapy with 3M™ Dermatac™ Drape.
    B) Initiation of 3M™ V.A.C.® Therapy.
    C) Wound appearance after four days of 3M™ V.A.C.® Therapy.
    D) Granulated wound after nine days of 3M™ V.A.C.® Therapy.

    Patient data and photos courtesy of Ralph Napolitano, Jr., DPM, CWSP, FACFAS; Orthoneuro; New Albany, OH.

  • Additional case studies brochure thumbnail

    NOTE: As with any case study, the results and outcomes should not be interpreted as a guarantee or warranty of similar results. Individual results may vary depending on the patient’s circumstances and condition.

    Read this and 8 other Dermatac Drape with V.A.C.® Therapy case studies (PDF, 5.5 MB)

Real world data demonstrated V.A.C.® Therapy delivers lower total cost to treat compared to other NPWT providers studied.³

In a retrospective analysis of 6,736 U.S. insurance claims in the outpatient setting, patients who received V.A.C.® Therapy had lower total and wound-related treatment costs than patients who received competitor NPWT, in all wound types across all time periods studied.

V.A.C.® Therapy patients had 30%–37% lower total and wound related costs across time periods and lower total out-of-pocket costs. Lower total costs to treat V.A.C.® Therapy patients driven by lower home health agency, skilled nursing facility, NPWT, and other expenses. NPWT charges represented only 3% of the total cost to treat.

The evidence behind V.A.C.® Therapy

In a retrospective analysis of 3,604 patients, when V.A.C.® Therapy was initiated early in acute (within the first 7 days) and chronic wounds (within the first 30 days) of varying size, the treatment time compared to late initiation (after the early time periods).

Early initiation of NPWT shows benefits across many care settings.¹²-¹⁴

Read the full study (PDF, 2.1 MB)

  • V.A.C.® Therapy brochure thumbnail
    What would 178 fewer days mean to your patients?

    The median days to reach significant closure (75% WSA [wound surface area reduction]) were 41.4 fewer days for acute wounds and 178 fewer days for chronic wounds compared to late initiation of NPWT.⁴

    Additionally, the early group was twice as likely to reach 75% surface area reduction as the late group for both acute and chronic wounds.

  • V.A.C.® Therapy reduction of length of stay chart
    Early initiation* of NPWT has been shown to reduce length of stay
    • Reduced inpatient days in acute and intensive care unit by at least 50%¹⁵
    • Reduced inpatient days in long term acute care by 30%¹⁴
    • Reduced homecare length of stay by 34% for surgical wounds¹³
    • Reduced homecare length of stay by 49% for pressure injuries¹³

    *Early: Acute wounds defined as NPWT initiated within the first 7 days. Chronic wounds are defined as NPWT initiated within the first 30 days. Late: NPWT initiation occurred after these periods.

Application guides and resources for V.A.C.® Therapy

  • �� Text on screen: This video is intended for clinicians. The ActiV.A.C.� Therapy System is an integrated negative pressure wound management system for use in acute, extended and home care settings. When used on open wounds, it is intended to create an environment that promotes wound healing by secondary or tertiary (delayed primary) intention by preparing the wound bed for closure, reducing edema, promoting granulation tissue formation and perfusion, and by removing exudate and infectious material. Open wound types include chronic, acute, traumatic, subacute and dehisced wounds, partial-thickness burns, ulcers (such as diabetic, pressure or venous insufficiency), flaps and grafts. When used on closed surgical incisions, it is intended to manage the environment of surgical incisions that continue to drain following sutured or stapled closure by maintaining a closed environment and removing exudate via the application of negative pressure wound therapy. Prior to use of the ActiV.A.C.� Therapy System, consult the product instructions for use and safety information provided with the device. Additional safety information specific to the ActiV.A.C.� Therapy System is available at the end of this video. Contact your local 3M representative if you have any questions before initiating therapy. Text on screen: 3M� ActiV.A.C.� Therapy System Clinician Instructional Video. A photo of the ActiV.A.C.� Therapy Unit with carrying case, 3M� V.A.C.� Drape, SensaT.R.A.C.� Pad, and 3M� V.A.C.� Granufoam� Dressing. This learning tool has been created to help you understand how to clearly operate the ActiV.A.C.� Therapy System so your patients can receive the proven wound healing benefits of 3M ActiV.A.C.� Therapy System. Text on screen: External Controls. j& To begin, ensure the ActiV.A.C.� Therapy System has been properly charged. A photo of the ActiV.A.C.� Therapy Unit with a blank touchscreen interface. The small LED Battery Charge Indicator will show amber if it's charging and green when fully charged. The LED Battery Indicator light, beside the lower left corner of the touchscreen interface, glows with an amber light. Suddenly, it illuminates green to show it is fully charged. To turn on the ActiV.A.C.� Therapy System, press and hold the power button on the front of the unit for two seconds, then release. A hand comes from off-screen and presses the power button on the unit, located on the lower left side of the front of the unit, beneath the touchscreen user interface. The touchscreen illuminates and the 3M logo appears on it, followed by information about the unit. Text on screen: Using the ActiV.A.C.� Therapy System. j& Once the ActiV.A.C.� Therapy System is powered up, you'll see the Home screen. A hand comes from off-screen and presses the OK button on the touchscreen to exit a warning display onscreen. The home screen appears on the screen. By pressing the On/Off button, you can stop and start the machine. A close-up of the home screen containing the On/Off button and the Audio Pause button. The Audio Pause button allows you to pause the sound for alarms that don't require immediate attention until the alarm sounds again. A hand comes from off-screen and presses the blue oval Audio Pause button on the touchscreen, located directly to the right of the On/Off button. A crescent shape in the bottom curve of the button illuminates green to indicate Audio Pause has been activated. A timer in the upper left corner indicates time left before alarms sound again. Text on screen: Critical alarms are not able to be paused. Press the Audio Pause button to turn audio alarms back on before the timer runs out. The hand again presses the Audio Pause button and the crescent darkens, losing its green glow. The timer in the upper left corner of the touchscreen also disappears. Text on screen: Help Menu. j& To access the Help menu, press the Question Mark button. A close-up of the touchscreen interface of the ActiV.A.C.� Therapy Unit. A green ring glows around the circular Question Mark button in the lower left corner of the touchscreen. NOTE: Consult the user manual guide provided with the ActiV.A.C.� Therapy System for further details. Select an option from the Help menu, then accept the disclaimer. A blue oval button, Operating Instructions, is selected. A disclaimer appears onscreen and the Next button glows with a green ring around it. The Operating Instructions menu appears. Press the Exit button at any time to return to the main Help menu. The Exit button, in the top right corner of the touchscreen, glows with a green ring around it. The Operating Instructions menu quickly changes to the main Help Menu. Here, you're also able to change the onscreen language by pressing the Globe and making a selection. The circular Globe button in the upper left corner of the touchscreen glows with a green ring around it. The main Help Menu quickly changes to a Language Menu where a rectangular box displays each available language and up and down arrows beside it allow the user to move through the available languages to make a selection. Text on screen: Clinician Mode. j& Within the Help menu, you may toggle between Clinician Mode and Patient Mode. A blue oval button, located on the upper right side of the main Help Menu screen, changes rapidly between Clinician Mode and Patient Mode. NOTE: The unit will automatically return to Patient Mode after approximately 15 minutes if there has been no touchscreen activity. Healthcare providers simply click the Clinician Mode button, then press and hold the OK button for five seconds to access the Clinician Mode menu. A close-up of the blue oval Patient and Clinician Modes button on the Help Menu screen. The button reads "Clinician Mode" and a green ring glows around it. The screen changes to a Clinician Mode screen with a warning that only authorized caregivers may continue. An oval OK button in the lower right corner glows with a green ring around it. After 5 seconds, the screen changes to the main Clinician Mode screen. j& Choose from the three menu options: On/Off, Utilities, and Therapy. The three oval buttons arrange in a pyramid onscreen, with the On/Off button at the top, the Utilities button on the left base, and the Therapy button on the right base. A green ring glows around each button as it is mentioned. In Utilities, you can change the date and time, screen brightness, region preferences, and toggle the AC Indicator Light on and off. A close-up of the main Utilities menu. As each button is mentioned, a green ring glows around it. The Time/Date button is at the upper left. The Brightness button is at the upper right. A crescent shape sits at the bottom curve of the Brightness button. It has been broken into three sections which glow depending on chosen screen brightness. The Region Settings button is located beneath the Time/Date button, and the AC Light button with crescent shape glows beneath the Brightness button. j& Text on screen: Therapy Menu. A hand comes from off-screen and presses the Therapy button on the Clinician Mode menu. A disclaimer appears. Text on screen: Therapy Settings. Carefully review V.A.C.� Therapy Safety Information and Clinical Guidelines before proceeding. Always follow physician orders. The hand presses the Next button at the bottom of the screen. In the Therapy menu, you have four options: Settings, Settings Guide, Seal Check�, and History. A close-up of the Therapy menu. As each button is mentioned, a green ring glows around it. The Settings button is in the upper left side with the Settings Guide button to its right. The Seal Check� button is below the Settings button with the History button located to its right. j& Settings allows you to adjust the therapy settings, including the pressure and intensity of the therapy and whether the therapy is continuous or intermittent. Four buttons appear on the Settings menu. As each button is mentioned, a green ring glows around it. The Pressure button is located at the top left with the Intensity button located to its right. A crescent shape sits at the bottom curve of the Intensity button. It has been broken into three sections which glow depending on chosen intensity. The Continuous button is located beneath the Pressure button. Below, the Continuous button's bottom crescent glows green, and the Intermittent button remains dark to its right. j& Intermittent adjusts the therapy time on and off settings. A close-up of the Intermittent menu. Plus and Minus toggle arrow buttons appear in the middle of the screen. Beside them, on the left, On Time Minutes are displayed. On the right, Off Time Minutes are displayed. To save your changes, press the Exit button. A green ring glows around the Exit button in the top right corner of the touchscreen. The Settings menu screen returns. Before exiting the Settings menu, you will be asked to confirm your settings. Press OK to return to the main Clinician Mode, or Back to make changes to the therapy settings. A confirmation screen appears, displaying the pressure, mode, and intensity for treatment of partial thickness burns. A green ring first glows around the OK button on the lower right of the screen, and then around the Back button on the lower left side of the screen. j& The Back button is selected and the screen returns to the main Clinician Mode menu. From there, the Therapy button is selected again. On the Therapy Settings screen, Next is selected to accept a disclaimer and the screen returns to the Therapy menu where the Settings Guide button is selected. Settings Guide allows you to select a therapy range according to the type of wound. A Select Wound Type screen appears. A rectangular box in the middle of the screen displays wound types. Up and down toggle arrows to the right of the box allow the user to scroll through available options. You'll be led through a series of screens to select the prescribed pressure setting and the therapy mode before confirming the selected settings. The screen scrolls through the pressure settings and therapy modes by use of the Next button before landing on the confirmation screen. The OK button on the confirm screen glows with a green ring around it. Select Seal Check� from the Therapy menu to ensure a proper dressing seal is in place. The Seal Check� button glows green on the Therapy menu and the screen changes to the Seal Check� screen. A graph displays leak rate on the left side of the screen and a blue oval Seal Audio button's bottom curve crescent glows green beside it to the right. Select History to view therapy history. The History button glows green on the Therapy menu and the screen changes to the Therapy History screen. Two blue oval buttons appear in the middle of the screen: View History on the left, and Export History on the right. To export the history data, simply plug in a USB device and click Export to USB. A pair of hands grasps the ActiV.A.C.� Therapy Unit and inserts a USB storage device into the unit's left side USB port. The touchscreen displays the Export to USB button in the middle of the screen. One hand presses the button. The screen changes to a USB Transfer screen with instructions on how to insert a USB device into the unit for export. The hand presses the Next button and the export begins. j& The export completes and the hand presses the OK button in the lower right corner of the touchscreen to continue. The screen returns to the Therapy History menu screen. To return to Patient Mode, press the Question Mark button from the Home screen, select Patient Mode, then OK. The Question Mark button in the lower left corner of the main Clinician Mode menu glows with a green ring around it. The Help Menu appears and Patient Mode is chosen. A directive displays to press OK to change to Patient Mode and the OK button's outer ring glows green. The screen returns to the main Patient Mode menu. j& Text: Changing the Canister. Before changing the Canister, make sure the therapy unit is completely turned off by pressing and holding the On/Off button for two seconds, then select Yes on the confirmation screen of the ActiV.A.C.� Therapy System. A hand comes from off-screen and presses the power button on the unit, located on the lower left side of the front of the unit, beneath the touchscreen user interface. The Confirmation screen appears, asking the user if they would like to turn the therapy unit off, and the Yes button is selected. The touchscreen goes dark as the unit turns off. Begin changing the Canister by sliding the locking clamps close to the tubing connector, and close both clamps. Disconnect the dressing tubing from the Canister tubing. The pair of hands each hold a tube, one coming from the Canister and one coming from the SensaT.R.A.C.� Pad. Each tube has a clamp and tubing connector. The tubes meet in the middle at the connected tubing connectors. The hands slide the clamps toward the tubing connectors. They compress the clamps and twist the tubing connectors and the tubes separate from each other. Depress the Canister latch release on the side of the Canister, and pull the Canister away from the therapy unit. Slide the new Canister over the square latch guide. You'll hear an audible click once the Canister is in place. The hands perform the Canister replacement as described. One hand pulls the latch release on the right side of the ActiV.A.C.� Therapy Unit while the other hand holds the unit in place. Then, it pulls the Canister directly off the unit. Then, the hand slides a new Canister over the Canister latch guide and into place. Reconnect the tubing and release both clamps. The hands now compress and twist the two tubing connectors back together. The hands unlock the clamps by opening them. j& Text on screen: Starting Therapy. j& Finally, press the On/Off button to start therapy. The Therapy Start screen will appear. A hand comes from off-screen and presses the power button on the unit, located on the lower left side of the front of the unit, beneath the touchscreen user interface. The touchscreen illuminates and the 3M logo appears on it, followed by information about the unit. Then, the Clinician Mode main menu appears. Therapy is chosen from this menu and then Therapy Settings. Next is clicked through a disclaimer screen. j& During therapy, you can view the Seal Check� feature to detect leaks, control the seal audio tone, and enter the Log menu. The Seal Check� button is chosen on the Therapy menu. The Seal Check� screen appears and displays a graph of leak rate on the left side of the screen and the Log and Seal Audio buttons on the right. Note, be sure to record the Canister change and number of foam pieces used during the dressing change in the Log menu and in the patient record. A close-up of the Item to Log screen. Two blue oval buttons appear in the middle of the screen: the Canister button on the left and the Dressing button on the right. Now, you can easily help patients receive positive clinical outcomes with the 3M� ActiV.A.C.� Therapy System. A photo of the ActiV.A.C.� Therapy Unit with carrying case, V.A.C.� Drape, SensaT.R.A.C.� Pad, and Granufoam� Dressing. Text on screen: Portable negative pressure wound therapy for wound management. 3M� ActiV.A.C.� Therapy System. Please refer to the user manual for further operational details and safety information sheet for indications, contraindications, warnings, and precautions related to V.A.C.� Therapy. These documents are provided with the ActiV.A.C.� Therapy System. 3M logo build: 3M Science. Applied to Life. Instructions for Use and Safety Information: As with any device, it is important to read and understand the detailed instructions for use and safety information applicable to the ActiV.A.C.� Therapy System. If you have product questions, please contact your local representative. NOTE: Specific indications, contraindications, warnings, precautions and safety information exist for these products and therapies. Please consult a clinician and product instructions for use prior to application. This material is intended for healthcare professionals. Rx only. � 2021 3M. All rights reserved. 3M and the other marks shown are marks and/or registered marks. Unauthorized use prohibited. Used under license in Canada. PRA-PM-ALL-00490 (04/21)

    ActiV.A.C. Therapy system clinician instructions  Use Brightcove to play the video!
    ActiV.A.C. Therapy System Clinician Instructions

    This video demonstrates how to operate the ActiV.A.C. Therapy System. Specific indications, contraindications, warnings, precautions and safety information exist for these products and therapies.

    Video 5:29 min

  • �� Text on screen: This video is intended for clinicians. Prior to use of the 3M"! V.A.C.� Ulta Therapy System, consult detailed product indications, safety information, and instructions contained in the V.A.C.� Ulta Therapy System Safety Information, V.A.C.� Ulta Therapy System User Manual, and 3M"! V.A.C. Veraflo"! Dressing Application provided in the dressing cartons. The V.A.C.� Ulta Therapy System is an integrated wound management system that provides Negative Pressure Wound Therapy (3M"! V.A.C.� Therapy) with an instillation option (3M"! Veraflo"! Therapy). V.A.C.� Therapy in the absence of instillation is intended to create an environment that promotes wound healing by secondary or tertiary (delayed primary) intentions by preparing the wound bed for closures, reducing edema, promoting granulation tissue formation and perfusion, and by removing exudate and infectious material. Veraflo Therapy is indicated for patients who would benefit from vacuum assisted drainage and controlled delivery of topical wound treatment solutions and suspensions over the wound bed. The V.A.C.� Ulta Therapy System with and without instillation is indicated for patients with chronic, acute, traumatic, sub-acute and dehisced wounds, partial thickness burns, ulcers (such as diabetic, pressure and venous insufficiency), flaps and grafts. V.A.C.� Therapy in the absence of instillation may also be used for: The temporary bridging of abdominal wall openings where primary closure is not possible and/or repeat abdominal entries are necessary and for open abdominal wounds with exposed viscera including, but not limited to, abdominal compartment syndrome. The intended care setting is a closely monitored area within the acute care hospital, such as the ICU. The abdominal dressing will most often be applied in the operating theater. The management of the environment of surgical incisions that continue to drain following sutured or stapled closure by maintaining a closed environment and removing exudate via the application of negative pressure wound therapy. Additional safety information specific to the V.A.C.� Ulta Therapy System is available at the end of this video. Contact your local representative if you have any questions before initiating therapy. j& Text on screen: 3M "! V.A.C.� Therapy on 3M "! V.A.C.� Ulta 4 Therapy System. Text on screen: Initiate V.A.C.� Therapy. A canister is attached to the V.A.C.� Ulta 4 Therapy System Unit. The light blue V.A.C.� Therapy button is highlighted and the default settings screen appears. Text on screen: Default settings. The green OK button is highlighted and therapy begins. The Exit button is highlighted and the Active Therapy home screen appears. To initiate V.A.C. Therapy, attach the 500-milliliter or 1,000-milliliter canister to the V.A.C.� Ulta 4 Therapy Unit. Press the light blue V.A.C.� Therapy button. Next, press the green OK button on the confirmation screen to accept default settings and begin V.A.C.� Therapy. Press the Exit button on the SEAL CHECK Leak Detector screen to go to the Active Therapy home screen. j& 3M logo with the words, "Science. Applied to life. "!" Text on screen: Instructions for Use and Safety Information: As with any device, it is important to read and understand the detailed instructions for use and safety information (including information on bleeding, exposed vessels and organs, and infection) applicable to your V.A.C.� Ulta Therapy Unit and dressing application that can be found with the therapy unit, disposables carton or at hcbgregulatory.3M.com. These sources provide information concerning the proper application of all 3M Dressings. If you have product questions or require additional product training, please contact your local 3M representative. Additional product information can be found at www.3M.com/medical. This material is intended for healthcare professionals. Rx only. � 2021 3M. All rights reserved. 3M and the other marks shown are marks and/or registered marks. Unauthorized use prohibited. Used under license in Canada. PRA-PM-ALL-00565 (11/21) KCI Part of 3M

    V.A.C.® Ulta 4 Therapy System video thumbnail  Use Brightcove to play the video!
    V.A.C.® Therapy on the 3M™ V.A.C.® Ulta 4 Therapy System

    This video provides an overview and directions to initiate V.A.C.® Therapy, which is used on the V.A.C.® Ulta 4 Therapy System.

    Video 0:40 min

  • (DESCRIPTION) Text, This video is intended for clinicians. Disclaimers. 3M V.A.C. Dressing Application with 3M Dermatac Drape Basic Technique. (SPEECH) [MUSIC PLAYING] The 3M Dermatac Drape is an accessory to 3M VAC Therapy Systems and is the first silicon acrylic hybrid drape uniting the necessary properties of a soft and skin-friendly drape with strong stable adhesion to provide the ideal balance for wound-healing support. (DESCRIPTION) Animated drape. (SPEECH) Dermatac Drape is easy to use and reduces the time associated with dressing changes compared to standard of care. Its unique combination improves handling, placement, and patient comfort, while providing periwound support. (DESCRIPTION) Text, Dressing Kit Components. Disclaimers. (SPEECH) The 3M Dermatac Drape and VAC Granufoam Dressing Kit includes 3M VAC Granufoam Dressing, the 3M Dermatac Drape, the sensor trackpad, and a VAC ruler with two foam quantity labels. The 3M Dermatac Drape can also be used with 3M VAC Whitefoam dressings. All components are disposable, single-use only, and packaged sterile. (DESCRIPTION) Wound Preparation. A clinician demonstrates on a model. (SPEECH) Before applying a new dressing, remove and discard the previous dressing per institution protocol. Thoroughly inspect the wound to ensure all pieces of dressing components have been removed. Perform a thorough wound and periwound area cleaning per physician order or institution protocol prior to each dressing application. Ensure adequate hemostasis has been achieved. (DESCRIPTION) Dressing Application for Single Wounds. (SPEECH) Shown here is a wound requiring a standard VAC dressing using Dermatac Drape. Assess the wound dimensions and pathology, including the presence of undermining or tunnels. (DESCRIPTION) The clinician measures a wound. (SPEECH) Do not place foam dressing into blind or unexplored tunnels. (DESCRIPTION) The clinician explores a wound tunnel. With scissors, they cut foam dressing. (SPEECH) Use VAC Whitefoam Dressing with explored tunnels. (DESCRIPTION) The clinician inserts foam dressing in an explored tunnel. (SPEECH) Cut the foam dressing to dimensions that will allow the foam to be placed gently into the wound without overlapping onto the skin. (DESCRIPTION) The clinician cuts foam dressing to size. Then, the clinician places the foam into the wound cavity. (SPEECH) Gently place the foam into the wound cavity, ensuring contact with all wound surfaces. Do not force foam dressing into any area of the wound. (DESCRIPTION) Text, Drape Application. When sizing, cut from handling bar to handling bar. (SPEECH) Trim Dermatac Drape to cover the VAC Dressing Foam and an additional 5 to 7-centimeter border of intact periwound tissue. Remove the release liner to expose the adhesive. (DESCRIPTION) Note: Patient's skin condition should be carefully monitored. To avoid trauma to the skin, do not pull or stretch the drape over the foam during drape application. (SPEECH) Place the adhesive face-down over the foam and apply the drape to cover the foam and intact skin, ensuring the drape covers at least a 5 to 7-centimeter border of intact periwound tissue. (DESCRIPTION) The clinician applies a drape. (SPEECH) While holding down the edge of the drape, remove the perforated handling bars from the drape. (DESCRIPTION) Text, Drape can be peeled back and re-applied during initial placement to address affected part of the dressing. (SPEECH) Smooth any wrinkles or creases in the dressing to prevent leaks. (DESCRIPTION) The clinician adjusts the drape and smooths out creases. (SPEECH) Pat down to ensure an inclusive seal. (DESCRIPTION) The clinician pats down the drape by smoothing with gloved fingers. Text, SensaTRAC Pad Application. (SPEECH) Now, choose the pad application site for the sensor trackpad. Pinch the drape and carefully cut in approximately 2.5-centimeter hole, not a slit, through the Dermatac Drape. The hole should be large enough to allow for removal of fluid and exudate. You do not need to cut into the foam. Apply the pad, which has a central disk and a surrounding outer adhesive skirt. Remove both backing layers 1 and 2 to expose the adhesive. Place pad opening in central disk directly over the hole in the drape. (DESCRIPTION) Refer to clinical guidelines. (SPEECH) Apply gentle pressure on the central disk and outer skirt to ensure complete adhesion of the pad. (DESCRIPTION) The clinician applies pressure with hands. (SPEECH) Pull back on the blue tab to remove the pad stabilization layer. (DESCRIPTION) Text, Prior to use, consult product instructions and prescribing information. (SPEECH) Connect the sensor trackpad tubing to the canister tubing and ensure the clamp on each tube is open. (DESCRIPTION) Review all V.A.C. Therapy System Information before initiating. (SPEECH) Position clamps away from the patient. Turn on power to the V.A.C. therapy unit. (DESCRIPTION) The clinician turns on a V.A.C. therapy unit, then selects On/Off. (SPEECH) Select prescribed therapy setting. (DESCRIPTION) Refer to unit specific guide. (SPEECH) Assess the dressing to ensure seal integrity. The dressing should be collapsed and have a wrinkled appearance. There should be no hissing sounds. (DESCRIPTION) 3M Science Applied to Life. (SPEECH) For more product demos and application techniques, visit 3M.com/medical.

    Dermatac Drape application video thumbnail  Use Brightcove to play the video!
    V.A.C.® Dressing Basic Application using Dermatac Drape

    This video demonstrates a V.A.C.® Therapy dressing application using a standard V.A.C.® Granufoam Dressing and Dermatac Drape – the innovative hybrid silicone-acrylic drape.

    Video 5:37 min

  • �� Text on screen: This video is intended for clinicians. Prior to the use of the 3M� V.A.C.� Therapy System, consult detailed product instructions and important prescribing information contained in the V.A.C.� Therapy Clinical Guidelines and the device specific user's guides. The V.A.C.� Therapy System is indicated for patients with chronic, acute, traumatic, subacute and dehisced wounds, partial thickness burns, ulcers (such as diabetic or pressure), flaps and grafts. V.A.C.� Therapy is contraindicated for: Patients with Malignancy in the wound. Untreated osteomyelitis. Note: Refer to Warnings section for osteomyelitis information. Non-enteric and unexplored fistulas. Necrotic tissue with eschar present. Note: After debridement of necrotic tissue and complete removal of eschar, V.A.C.� Therapy may be used. Sensitivity to silver (3M� V.A.C.� Granufoam Silver� Dressing only). Additional indication and safety information specific to the V.A.C.� Therapy System is available at the end of this video. Contact your local representative if you have any questions before initiating therapy. j& Text on screen: 3M� V.A.C.� Dressing Application Small Wound. Three different foam types used with the V.A.C.� Therapy System appear on screen. An animated cross-section of an open wound is treated with the V.A.C.� Therapy System. Text on screen: Wounds smaller than the SensaT.R.A.C.� Pad or less than four centimeters can easily be treated with V.A.C.� Therapy with the application of the small wound technique, while also helping you protect the patient's fragile periwound tissue and prevent maceration. The 3M� V.A.C.� Therapy System is an integrated wound management system for use in acute, extended, and home care settings. When used on open wounds, it is intended to create an environment that promotes wound healing by secondary or tertiary intention by preparing the wound bed for closure, reducing edema, promoting granulation tissue formation and perfusion, and removing exudate and infectious material. j& Text on screen: Dressing Kit Components. 3M� V.A.C.� Dressing Kit. Items appear on screen, including the 3M� V.A.C.� Granufoam� Dressing, the 3M� V.A.C. Whitefoam� Dressing, the 3M� V.A.C.� Granufoam Silver� Dressing, the SensaT.R.A.C.� Pad, the 3M� V.A.C.� Drape or 3M� V.A.C. Dermatac� Drape, and the 3M� V.A.C.� Ruler with two Foam Quantity Labels. Text on screen: Note: Always consult a physician and review and follow V.A.C.� Therapy Safety Information, V.A.C.� Therapy Unit Instructions and appropriate sections of the V.A.C.� Therapy Clinical Guidelines prior to use. The components of V.A.C.� Dressing Kits are: the 3M� V.A.C.� Dressing, which includes the 3M� V.A.C.� Granufoam� Dressing, the 3M� V.A.C. Whitefoam� Dressing, and the 3M� V.A.C.� Granufoam Silver� Dressing; the SensaT.R.A.C.� Pad, the 3M� V.A.C.� Drape, or 3M� V.A.C. Dermatac� Drape, and a 3M� V.A.C.� Ruler with two Foam Quantity Labels. All components are disposable, single-use only, and packaged sterile. j& Text on screen: Wound Preparation. Demonstrated here on a sacral wound ulcer. Warning: Review all V.A.C.� Therapy System Safety Information before beginning Wound Preparation. Refer to Warnings, Bleeding section in the V.A.C.� Therapy System Safety Information and V.A.C.� Granufoam� Dressing Application Instructions. A medical professional tends to a wound on a practice mannequin on an operating table in a hospital setting. The medical professional removes existing dressing from the wound. The medical professional inspects the wound and cleans it according to institutional protocol. Before applying a new dressing, remove and discard the previous dressing per institution protocol. Thoroughly inspect the wound to ensure all pieces of dressing components have been removed. Perform a thorough wound and periwound area cleaning per physician order or institution protocol prior to each dressing application. Ensure adequate hemostasis has been achieved. j& Text on screen: V.A.C.� Dressing Application for Single Wounds. A medical professional tends to a wound on a practice mannequin's foot on an operating table. The medical professional opens a packet of 3M� Cavilon� No Sting Barrier Film and applies it to the periwound skin. Text on screen: Note: If adjunct materials are utilized under the V.A.C.� Dressing, they must be meshed or fenestrated to allow for effective exudate removal and negative pressure delivery. Record the total number of pieces of foam used in the wound and document this on the Foam Quantity Label and in the patient's chart. The medical professional uses scissors to cut a hole in the middle of the V.A.C.� Drape. They place the hole in the drape directly over the wound and peel back layers of adhesive backing. They gently press the adhesive into place. Shown here is a small wound requiring a standard V.A.C. dressing. Prepare the periwound area by applying a protective skin barrier preparation, such as 3M� Cavilon� No Sting Barrier Film. j& Picture frame or window pane the wound with a hydrocolloid dressing, or another vapor-permeable adhesive film dressing, such as V.A.C. Drape, or 3M� Tegaderm� Transparent Film Dressing. (crinkling) j& The medical professional uses scissors to cut a piece of dressing foam to a desired size. Text on screen: Do not cut the foam over the wound, as fragments may fall into the wound. Away from the wound site, rub foam edges to remove any fragments or loose particles that may fall into or be left in the wound upon dressing removal. The medical professional continues to cut the foam away from the wound and gently rubs the edges to remove any excess. Cut dressing foam to dimensions that will allow the foam to be placed gently into the wound, but not overlap onto intact skin. j& Text on screen: Assure the foam does not extend onto intact skin, that it is positioned on the product used to "picture frame" the wound and protects the intact skin. Note: Ensure foam-to-foam contact between adjacent pieces of foam for even distribution of negative pressure. Do not force dressing foam into any area of the wound. The medical professional places the foam into the wound cavity. The medical professional places a larger, circular piece of foam over the first piece of foam in the wound. Gently place the foam into the wound cavity, ensuring contact with all wound surfaces. To accommodate the size of the SensaT.R.A.C.� Pad, cut another piece of foam large enough to extend two- to three-centimeters beyond the SensaT.R.A.C.� Pad, and lay the foam in the wound. j& Text on screen: Drape application. The medical professional peels an adhesive backing off of the drape and places it over both pieces of foam. They gently press down to secure the drape to the surrounding skin. Text on screen: Note: Patient's skin condition should be carefully monitored. The medical professional continues to remove layers of adhesive backing and gently presses the drape into place over the skin, ensuring a seal. Trim and place the drape to cover the foam dressing and an additional three- to five-centimeter border. j& (crinkling) j& Text on screen: SensaT.R.A.C.� Pad Application. The medical professional pinches the V.A.C.� Drape and cuts a small hole over the foam. Text on screen: Cut a hole, not a slit. Note: Do not cut off the pad or insert the tubing directly into the foam dressing. This may occlude the tubing and cause the V.A.C.� Therapy Unit to alarm. Pinch the V.A.C. drape and carefully cut an approximately 2.5-centimeter hole, not a slit, through the V.A.C. drape. The hole should be large enough to allow for removal of fluid and exudate. You do not need to cut into the foam. j& The medical professional holds the SensaT.R.A.C.� Pad over the wound area as they prepare to apply it. They remove two backing layers and place the adhesive side of the pad directly over the hole in the drape. Text on screen: Note: To prevent periwound maceration with wounds that are smaller than the central disc of the pad, it is very important that the central disc lay on top of foam only. It may be necessary to augment the V.A.C.� Dressing that is in the wound with an additional piece of foam cut 1-2cm larger than the diameter of the central disc. If this is used, please ensure the periwound skin is protected prior to foam augmentation. The medical professional gently presses down on the SensaT.R.A.C.� Pad to secure it to the dressing. Text on screen: Please refer to the V.A.C.� Therapy Clinical Guidelines for additional dressing application techniques. The medical professional pulls on a blue tab on the SensaT.R.A.C.� Pad to remove the pad stabilization layer. They gently press down on the drape to secure it to the area. Apply the pad, which has a central disc, and a surrounding outer adhesive skirt to the larger piece of the foam. Remove both backing layers one and two to expose adhesive. j& Place pad opening in the central disc directly over the hole in the drape. Apply gentle pressure on the central disc and outer skirt to ensure complete adhesion of the pad. j& Pull back on the blue tab to remove the pad stabilization layer. j& Text on screen: Begin Therapy. Label dressing as per institutional protocol. Warning: Review all V.A.C.� Therapy System Information before initiating V.A.C.� Therapy. Note: If the V.A.C.� Canister is not fully engaged, the V.A.C.� Therapy Unit will alarm. The medical professional connects SensaT.R.A.C.� tubing and Canister tubing. They open clamps on both tubes and position them away from the patient. The medical professional presses the power button on the V.A.C.� Therapy Unit and touches a button on the screen that reads "On/Off". Connect SensaT.R.A.C.� Pad tubing to canister tubing. j& And ensure clamp on each tube is open. j& Position clamps away from the patient. Turn on power to the V.A.C.� Therapy unit. j& Select prescribed therapy setting. (gentle whirring) j& Text on screen: Note: Refer to unit specific user guide or manual and/or quick reference guide for information regarding alarms. If a leak source is identified, patch with additional drape to ensure seal integrity. Use the Seal Check� feature to verify that the rate of air leakage is below the alarm threshold. Negative vacuum pressure is applied and the dressing has a wrinkled appearance. The medical professional examines the dressing and gently presses down to make sure therapy is working. Text on screen: If there is evidence of a leak, check SensaT.R.A.C.� Pad and drape seal, tubing connections, canister insertion, and ensure clamps are open. Assess dressing to ensure seal integrity. The dressing should be collapsed and have a wrinkled appearance. There should be no hissing sounds. For more product demos and application techniques, visit 3M.com/medical. 3M� logo with the words, "Science. Applied to life." Text on screen: Instructions for Use and Safety Information: As with any device, it is important to read and understand the detailed instructions for use and safety information (including information on bleeding, exposed vessels and organs, and infection) applicable to your V.A.C.� Therapy unit and dressing application that can be found with the therapy unit, disposables carton or in the V.A.C.� Therapy Clinical Guidelines (www.3M.com/medical). These sources provide information concerning the proper application of all V.A.C.� Therapy Dressings, including advanced applications and techniques. If you have product questions or require additional product training, please contact your V.A.C.� Therapy local representative. Additional product information can be found at www.3M.com/medical. Note: Specific indications, contraindications, warnings, precautions and safety information exist for these products and therapies. Please consult a clinician and product instructions for use prior to application. This material is intended for healthcare professionals. Rx only. 2021 3M. All rights reserved. 3M and the other marks shown are marks and/or registered marks. Unauthorized use prohibited. Used under license in Canada. PRA-PM-ALL-00552 (05/21) KCI part of 3M.

    Application mushroom technique video thumbnail.  Use Brightcove to play the video!
    Application tips: V.A.C.® Dressing Application Mushroom Technique on Small Wounds

    This video provides application technique tips for applying V.A.C.® Dressings using the "mushroom" technique on small wounds.

    Video 5:10 min


10 million wounds treated worldwide with V.A.C.® Therapy¹

Since its introduction in 1995, V.A.C.® Therapy has been selected to treat more than 10 million wounds worldwide¹.

Training opportunities and educational resources

Deepen your clinical expertise with training opportunities and educational resources designed especially for you.
3M webinars and archived events can help keep you up to date with the latest product guidelines and scientifically supported standards of care.

Image of a nurse instructing a patient on how to use the Snap Therapy System.

Ready to try V.A.C.® Therapy?

See how our proprietary combination of products and technology can help you manage wound care the smart way.

REQUEST A DEMO

Manage a wide range of wounds with V.A.C.® Therapy

  • close up of a diabetic foot ulcer that is not infected
    Diabetic foot ulcers (DFUs)

    In a randomized controlled trial (V.A.C.® Therapy: n=169, AMWT: n=166), V.A.C.® Therapy was associated with a significantly greater proportion of DFUs achieving complete closure and fewer amputations at 112 days compared to advanced moist wound therapy (AMWT).¹⁶

    Learn more about Diabetic foot ulcers management

  • close up of pressure ulcer
    Pressure injuries

    Discover the difference V.A.C.® Therapy solutions can make, creating an environment that promotes wound healing.

    Learn more about pressure injury management

  • V.A.C.® Therapy provides negative pressure wound therapy for traumatic wounds and partial-thickness burns to create an environment that promotes wound healing. This helps draw wound edges together, remove infectious materials and promote granulation tissue formation.

    Learn more about traumatic wound management

Explore additional 3M Negative Pressure Wound Therapies

  • Veraflo Therapy combines the benefits of NPWT with automated instillation and dwell of topical wound solution to provide simultaneous cleansing and granulation tissue formation.*¹⁷,¹⁸

    *Results have not been confirmed in human studies.

    Learn more about Veraflo Therapy

  • Prevena Incision Management System manages the environment of closed surgical incisions and removes fluid away from surgical incisions via the application of continuous negative pressure.

    Learn more about Prevena Therapy

  • AbThera Therapy System incorporates all the functional elements of an optimal temporary closure device to help protect abdominal contents from the external environment, allowing rapid access for re-entry, medial tension, and fluid removal.

    Learn more about AbThera Therapy

  • Snap Therapy is a discreet, single-use system that preserves patient mobility and is ideal for low-to-moderate exuding wounds.

    Learn more about Snap Therapy

Advanced technology, support and education

  • 3M™ Express

    Easily initiate V.A.C.® Therapy and Veraflo™ Therapy orders, get prescriptions signed via electronic signature and track order authorization online, in a secure and HIPAA compliant environment.
     

    • Place and track orders for V.A.C.® Therapy rental units, supplies, and disposables
    • Request service, pick-ups, and discontinuation of therapy
    • Access inventory management reports for V.A.C.® Therapy
    • V.A.C.® Therapy orders are released on average 9.7 hours faster19 than non-electronic orders.20
    • Access inventory management reports for the
      3M™ V.A.C.® Ready Care Program
    • Contact Support 1-800-275-4524 ext. 41858

    Enroll or log in to 3M Express

  • MyWoundHealing™ Mobile App for Patients

    Welcome to the next step in your healing journey. Use the MyWoundHealing™ Mobile App to help manage your V.A.C.® Therapy. We're here to support you when you need us most. Having a wound can be a challenging and scary experience, but your doctor feels that V.A.C.® Therapy is an appropriate way to manage your wound. This site was developed to help you better understand V.A.C.® Therapy and provide you with best use practices once the therapy is prescribed by your doctor.

    Key Features of MyWoundHealing:

    • Track your progress of the wound
    • Get help with your device regarding alarms, alerts, troubleshooting support
    • Easily reorder supplies    
    • Education on V.A.C.® Therapy 

    Learn more about MyWoundHealing™ App
    Download MyWoundHealing™ App

  • iOn Progress™ Remote Therapy Monitoring System for Prescribers

    We wrap your patient in support, striving to make this short moment in their recovery journey the least intrusive as possible. We do this, as allowed by their benefit plan, by giving them on-demand access to a team of  Virtual Therapy Specialists. This team is extensively trained in high risk patient communication and provides your patient another resource during their NPWT journey.

    This way, you can focus on what you need to get the wound healed and we can help them overcome the daily hurdles NPWT patients experience.

    In doing so, together we hope to reduce out of pocket expenses for patients and shorten their time on NPWT.

    81% of patients use therapy >16 hours after an adherence call.21

    Learn more about 3M iOn Progress™ Remote Therapy Monitoring System

  • Technical support

    Call 1-800-275-4524, x3 for questions and assistance troubleshooting our therapy units.

    Call 1-800-275-4524, x3 for questions and assistance troubleshooting our therapy units.

Looking for more information?

  • 3M is committed to providing customer service, including product reimbursement education and resources, to clinical providers and healthcare facilities that use qualified 3M products.

  • We are here to help! Get in touch with our customer support team for advice about our products and how to use them.

  • View our advanced wound product & NPWT product portfolio and browse our product catalog.

  • Find Instructions for Use to easily access documents for specific 3M Health Care products.


  • References

    1. 3M. Cumulative NPWT Wounds. 2018.

    2. Page JC, Newsander B, Schwenke DC, Hansen M, Ferguson J. Retrospective analysis of negative pressure wound therapy in open foot wounds with significant soft tissue defects. Adv Skin Wound Care. 2004;17(7):354-364.

    3. Law A L. Krebs B. Karnik B. Griffin L. Comparison of Healthcare Costs Associated With Patients Receiving Traditional Negative Pressure Wound Therapies in the Post Acute Setting. Cureus 12(11): e11790.

    4. Miller-Mikolajczyk C, Achi J, James R. Real world use: comparing early versus late initiation of negative pressure wound therapy on wound surface area reduction in patients at wound care clinics. Poster presented at The Wound Ostomy and Continence Nurses Society Annual Conference, June 22-26, 2013. Seattle, Washington.

    5. KCI. Percentage of V.A.C. Therapy Articles vs. Comp Articles. May 7, 2020

    6. Orgill DP, Manders EK, Sumpio BE, et al. The mechanisms of action of vacuum assisted closure: more to learn. Surgery. 2009 Jul;146(1):40-51.

    7. Saxena V, Hwang CW, Huang S, Eichbaum Q, Ingber D, Orgill DP. Vacuum-assisted closure: microdeformations of wounds and cell proliferation. Plast Reconstr Surg. 2004 Oct;114(5):1086-96; discussion 1097-8.

    8. McNulty AK, et al. Effects of negative pressure wound therapy on the fibroblast viability, chemotactic signaling and proliferation in a provisional wound (fibrin) matrix. WOUNDS. 2007; 15:838-‐846.

    9. Kilpadi DV, Kauffman C. Negative pressure wound therapy (NPWT) systems: ability to deliver prescribed negative pressure (NP) to the wound site. Paper presented at: Symposium on Advanced Wound Care Spring Meeting; April 23-27, 2014; Orlando, FL. Simulated wound bed pressures were measured under combinations of simulated wound-fluid flow rates. VAC therapy achieved acceptable levels of target NP in 9 out of 9 test combinations versus competitor product, which delivered lower than prescribed in 6 out of the 9 tested combinations.

    10. Kilpadi DV, Kauffman C. Comparing fluid removal by negative pressure wound therapy systems from simulated wound sites. Paper presented at: 36th John A. Boswick, MD Burn and Wound Care Symposium; February 15-19, 2014; Maui, HI.

    11. Desvigne, M. Initial Experiences Applying Negative Pressure Wound Therapy with a Novel Drape Containing an Acrylic and Silicone-based Adhesive. Poster Presented at the SAWC Fall Meeting, Las Vegas, NV. Oct 2019.

    12. Baharestani MM. Driver VR. Optimizing clinical and cost effectiveness with early intervention of V.A.C.® Therapy. Ostomy Wound Manage. 2008;54(11 Suppl):1-15.

    13. Baharestani MM, Houliston-Otto DB, Barnes S. Early versus late initiation of negative pressure wound therapy: examining the impact home care length of stay. Ostomy Wound Manage. 2008; 54(11 Suppl):48-53.

    14. Driver VR, de Leon JM. Health economic implications for wound care and limb preservation. J Managed Care Med. 2008; 1(11):13-19.

    15. Kaplan M, Daly D, Stemkowski S. Early intervention of negative pressure wound therapy using vacuum-assisted closure in trauma patients: impact on hospital length of stay and cost. Adv Skin Wound Care. 2009;3(22):128-132.

    16. Blume PA, Walters J, Payne W, Ayala J, Lantis J. Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial. Diabetes Care. 2008;31(4):631-636.

    17. Lessing C, Slack P, Hong KZ, Kilpadi D, McNulty A. Negative Pressure Wound Therapy With Controlled Saline Instillation (NPWTi): Dressing Properties and Granulation Response In Vivo. Wounds. 2011 Oct;23(10):309-19. PMID: 25881108.

    18. Carroll C, Ingram S. Comparison of Topical Wound Solutions for Negative Pressure Wound Therapy with Instillation: Effect on Granulation in an Excisional Non-Infected Acute Porcine Wound Model, Poster Presentation at SAWC, Oct 2017.

    19. Data pulled January 1, 2020 – August 31, 2020

    20. 3M. iOnHealingOrderstoRelease_Sept 2020_Internal Report. 25SEP2020.

    21. KCI. National iOn Progress RTM Dashboard. Cutameen/RTM_FINAL_TD4_Tables. [Dec 2016-Oct 2022]