3M™ ActiV.A.C. Therapy System with V.A.C.® Granufoam™ Bridge Dressing applied to DFU

Reimagine wound care. One patient at a time.

Each patient and wound is unique and deserves customized care. Our comprehensive negative pressure wound therapy solutions enable you to provide wound management options based on each patient’s needs.


3M Negative Pressure Wound Therapy (NPWT)

  • The way you treat every patient is as unique as they are — and no two wounds, just like no two people, are exactly the same. With 3M’s scientifically engineered negative pressure wound therapy solutions and support, you can reimagine the way you approach wound care. The 3M NPWT portfolio provides a wide range of wound management options, which have been shown in comparative clinical studies to help reduce the cost of care and improve patient outcomes.1-3

What is Negative Pressure Wound Therapy?

  • Applying 3M™ V.A.C.® Via Granufoam™ Spiral Dressing to ankle

    Negative Pressure Wound Therapy creates an environment that promotes the wound healing process. The application of negative pressure to a wound also assists with the removal of wound fluids, which can include infectious materials.


    Since the initial US clearance for commercialization of NPWT in 1995, NPWT has been used effectively in a wide variety of acute and chronic wounds.4 While NPWT was initially available only for inpatient wound treatment, over time, a variety of portable NPWT systems have been developed for use across the continuum of care.


    3M NPWT solutions come in all shapes and sizes—ranging from durable devices with multiple therapy modalities, to portable and disposable units that can fit in the palm of your hand.

3M Negative Pressure Wound Therapy

At 3M, we continue to develop new technologies and therapies designed to make wound healing manageable for you as caregivers and more comfortable for patients around the world. 3M NPWT have evolved beyond the standard 3M™ V.A.C.® Therapy.

NOTE: Specific indications, limitations, contraindications, warnings, precautions, and safety information exist for these products and therapies. Please consult a clinician and product Instructions for Use prior to application. This material is intended for healthcare professionals. Rx only.

  • 3M™ V.A.C.® Therapy

    An integrated wound management system designed and clinically shown to create an environment that promotes wound healing. V.A.C.® Therapy has demonstrated in published studies the potential to help reduce hospitalization time and risk of complications.5,6

    • Consistently delivers the prescribed programmed amount of negative pressure
    • Creates an environment to promote wound healing
    • Reducing therapy days for post-acute
      patients has been shown7

    Learn more about V.A.C.® Therapy 

  • 3M™ Veraflo™ Therapy

    Veraflo Therapy combines the benefits of NPWT with automated instillation and dwell of topical wound solution to provide simultaneous cleansing and granulation tissue formation.

    • Disrupt the formation of bioburden while stimulating granulation tissue formation
    • Prepare wounds for closure, maximize patient comfort, and has been shown in comparative clinical studies to have the potential to lower the total cost of care8

    Learn more about Veraflo Therapy

  • 3M™ Prevena™ Therapy

    Prevena Therapy uses Negative Pressure Therapy to manage the environment of closed surgical incisions via the application of continuous negative pressure therapy.

    • Helps hold incision edges together and decrease the lateral tension of sutured/stapled incisions
    • Removes fluid and infectious material away from the incision
    • In a multi-center randomized controlled trial, Prevena Therapy was shown to help reduce the risk of 90-day surgical site complications, readmissions, and surgical site costs vs. silver-impregnated dressings9,10

    Learn more about Prevena Therapy

  • 3M™ AbThera™ Therapy

    AbThera Therapy helps protect abdominal contents from the external environment, allows rapid access for re-entry, provides medial tension, and fluid removal. It helps draw wound edges together and helps to achieve primary fascial closure.

    In two separate studies, when compared to Barker's vacuum pack technique, AbThera Therapy demonstrated greater reduction in 30-day11 and 90-day all-cause mortality.12

    Learn more about AbThera Therapy

  • 3M™ Snap™ Therapy

    Snap Therapy System is a discreet, mechanically powered, single-use system that preserves patient mobility and is ideal for low-to-moderate exudating wounds.

    Customizable dressings to address even the most difficult anatomies, such as diabetic foot ulcers.

    Learn more about Snap Therapy

NPWT offers a wide range of solutions for different wound types

3M’s comprehensive NPWT portfolio helps promote a healing environment for many different types of wounds across multiple care settings.

2,000+ peer-reviewed publications

on 3M Negative Pressure Wound Therapy

Professional training opportunities and educational resources

Deepen your clinical expertise with training opportunities and educational resources designed especially for you. 3M webinars and archived events can help keep you up to date with the latest product guidelines and scientifically supported standards of care.

  • Practical Application Techniques of NPWTi-d and a Hybrid Drape
    New Users: Practical Application Techniques of NPWTi-d and a Hybrid Drape

    This webinar focuses on providing new instillation therapy adopters with the basics for a successful dressing application: including live dressing/therapy applications on anatomical models, sharing case examples, and a discussion of wound assessment and dressing selection criteria. Watch free webinar (50 min).
    Presenter: Ralph J. Napolitano, Jr., DPM, CWSP, FACFAS

    Viewing on desktop? Register/Login to view the course

    Get the iOS app or the Android app to view the course on mobile

  • Image of a laptop on a desk with books, a lamp, a folder and a coffee cup
    Develop with 3M℠ Health Care Academy

    Increase your knowledge of the latest techniques and training with the wide range of courses available on 3M℠ Health Care Academy. Discover online learning that's right for you.

    Viewing on desktop? Register/Login to view all courses

    Get the iOS app or the Android app to view all courses on mobile

Advanced technology, support and education

  • 3M™ Express

    Easily initiate V.A.C.® Therapy and Veraflo™ Therapy orders, get prescriptions signed via electronic signature and track order authorization online, in a secure and HIPAA compliant environment.

    • Place and track orders for V.A.C.® Therapy rental units, supplies, and disposables
    • Request service, pick-ups, and discontinuation of therapy
    • Access inventory management reports for V.A.C.® Therapy
    • V.A.C.® Therapy orders are released on average 9.7 hours faster16 than non-electronic orders.17
    • Access inventory management reports for the 
      3M™ V.A.C.® Ready Care Program
    • Contact Support 1-800-275-4524 ext. 41858

    Enroll or log in to 3M Express


  • MyWoundHealing™ Mobile App for Patients

    Welcome to the next step in your healing journey. Use the MyWoundHealing™ Mobile App to help manage your V.A.C.® Therapy. We're here to support you when you need us most. Having a wound can be a challenging and scary experience, but your doctor feels that V.A.C.® Therapy is an appropriate way to manage your wound. This site was developed to help you better understand V.A.C.® Therapy and provide you with best use practices once the therapy is prescribed by your doctor.

    Key Features of MyWoundHealing:

    • Track your progress of the wound
    • Get help with your device regarding alarms, alerts, troubleshooting support
    • Easily reorder supplies    
    • Education on V.A.C.® Therapy 

    Learn more about  MyWoundHealing™ App
    Download MyWoundHealing™ App

  • iOn Progress™ Remote Therapy Monitoring System for Prescribers

    We wrap your patient in support, striving to make this short moment in their recovery journey the least intrusive as possible. We do this, as allowed by their benefit plan, by giving them on-demand access to a team of Virtual Therapy Specialists. This team is extensively trained in high risk patient communication and provides your patient another resource during their NPWT journey.

    This way, you can focus on what you need to get the wound healed and we can help them overcome the daily hurdles NPWT patients experience.

    In doing so, together we hope to reduce out of pocket expenses for patients and shorten their time on NPWT.

    81% of patients use therapy >16 hours after an adherence call.18

    Learn more about 3M iOn Progress™ Remote Therapy Monitoring System

  • Technical support

    Call 1-800-275-4524, x3 for questions and assistance
    troubleshooting our therapy units.

    Technical support

    Call 1-800-275-4524x3,  for questions and assistance
    troubleshooting our therapy units.

Looking for more information?

  • 3M is committed to providing customer service, including product reimbursement education and resources, to clinical providers and healthcare facilities that use qualified 3M products.

  • We are here to help! Get in touch with our customer support team for advice about our products and how to use them.

  • View our advanced wounds and NPWT portfolios and browse our product catalog.

  • Find Instructions for Use to easily access documents for specific 3M Health Care products.

  • References

    1. Yang CK, Alcantara S, Goss S, Lantis JC 2nd. Cost analysis of negative-pressure wound therapy with instillation for wound bed preparation preceding split-thickness skin grafts for massive (>100 cm(2)) chronic venous leg ulcers. J Vasc Surg. 2015 Apr;61(4):995-9.

    2. Law A, Cyhaniuk A, Krebs B. Comparison of health care costs and hospital readmission rates associated with negative pressure wound therapies. Wounds. 2015 Mar;27(3):63-72.

    3. Kwon J, Staley C, McCullough M, Goss S, Arosemena M, Abai B, Salvatore D, Reiter D, DiMuzio P. A randomized clinical trial evaluating negative pressure therapy to decrease vascular groin incision complications. J Vasc Surg. 2018 Dec;68(6):1744-1752.

    4. Willy C, Voelker HU, Englehardt M. Literature On the Subject of Vacuum Therapy: Review and Update 2006. European Journal of Trauma and Emergency Surgery. 2007;33:33-39.

    5. Law A L Krebs B. Karnik B. Griffin L. Comparison of Healthcare Costs Associated With Patients Receiving Traditional Negative Pressure Wound Therapies in the Post Acute Setting. Cureus 12(11): e11790. DOI 10.7759/cureus.11790.

    6. Page JC, Newsander B, Schwenke DC, Hansen M, Ferguson J. Retrospective analysis of negative pressure wound therapy in open foot wounds with significant soft tissue defects. Adv Skin Wound Care/ 2004;17(7):354-364.

    7. Baharestani MM. Driver VR. Optimizing clinical and cost effectiveness with early intervention of V.A.C.® Therapy. Ostomy Wound Manage. 2008;54(11 Suppl):1-15.

    8. Kim PJ, Lookess S, Bongards C, Griffin LP, Gabriel A. Economic model to estimate cost of negative pressure wound therapy with instillation vs control therapies for hospitalised patients in the United States, Germany, and United Kingdom. International Wound Journal. 2022 May;19(4):888-894.

    9. Higuera-Rueda C, et al. The Effectiveness of Closed Incision Negative Pressure Therapy versus Silver-Impregnated Dressings in Mitigating Surgical Site Complications in High-Risk Patients after Revision Knee Arthroplasty: The PROMISES Randomized Controlled Trial. J Arthroplasty. 2021;36(7S):S295-S302.e14.

    10. Cooper HJ, Bongards C, Silverman RP. Cost-Effectiveness of Closed Incision Negative Pressure Therapy [PREVENA] for Surgical Site Management After Revision Total Knee Arthroplasty: Secondary Analysis of a Randomized Clinical Trial. Journal of Arthroplasty. 2022 Aug;37(8S):S790-S795.

    11. Cheatham ML, et al. Prospective Study Examining Clinical Outcomes Associated with a Negative Pressure Wound Therapy System and Barker’s Vacuum Packing Technique. World Journal of Surgery. 2013 Sep;37(9):2018-30.

    12. Kirkpatrick AW, Roberts DJ, Faris PD et al. Active Negative Pressure Peritoneal Therapy After Abbreviated Laparotomy: The Intraperitoneal Vacuum Randomized Controlled Trial. Ann Surg 2015;262:38-46.

    13. Lin KC, Li YS, Tarng YW. Safety and Efficacy of Prophylactic Closed Incision Negative Pressure Therapy after Acute Fracture Surgery. Injury. 2020 Aug;51(8):1805-1811.

    14. Baharestani MM, Houliston-Otto DB, Barnes S. Early versus late initiation of negative pressure wound therapy: examining the impact on home care length of stay. Ostomy Wound Management. 2008 Nov;54(11):48-53.

    15. Blume PA, Walters J, Payne W, Ayala J, Lantis J. Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial. Diabetes Care. 2008;31:631-636.

    16. Data pulled January 1, 2020-August 31, 2020

    17. 3M.iOnHealingOrderstoRelease_Sept2020_InternalReport. 25SEP2020.

    18. KCI. National iOn Progress RTM Dashboard. Cutameen/RTM_FINAL_TD4_Tables. [Dec 2016-Oct 2022]