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Surgeons using Prevena Therapy on a patient

Help advance the standard of care with 3M™ Prevena™ Therapy

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What is Prevena Therapy?

  • (SPEECH) Prevena Incision Management System, Mechanism of Action. Despite advancements in surgical procedures to address the needs of a changing population, surgical incision closure techniques utilizing sutures and staples remain conventional practice. In certain high risk patients and procedures, this surgical technique may lead to postoperative complications and increases in cost of care. Current treatment standards for incision management still rely on conventional dressings, such as gauze, following primary closure. These traditional dressings are passive therapies that provide minimal protection from external infectious sources. Surgical Site Infections or SSIs represent up to 22% of all health care associated infections. SSIs can increase the average length of hospital stay to an extra nine and half days at an additional cost of $38,000. Similarly, post-operative dehiscence has been shown to extend the average length of hospital stay by almost nine and half days at an increased cost of $40,000. The Prevena Incision Management System manages and helps protect a surgical incision by helping to hold incision edges together, removing fluids and infectious materials, acting as a barrier to external contamination, and delivering continuous negative pressure at -125 millimeters of mercury up to seven days. The Prevena Incision Management System is intended to manage surgical incisions that continue to drain following sutured or stapled closure by maintaining a closed environment and removing exudate via the application of negative pressure wound therapy. For surgical procedures that do not require dressing customization, the 3M Prevena Peel and Place Dressing is available in a variety of sizes. The adhesive film secures a dressing to the site and is easily applied in the operating room. The stabilization layer prevents wrinkling during application to create a robust seal around the incision. The protective shell is flexible to allow the dressing to conform to most surgical locations, and acts as a barrier to external contamination. The skin interface layer wicks fluid away from the surface and contains 0.019% ionic silver to help and control growth in the interface layer. The benefits of 3M Prevena Therapy are not limited to barrier protection of the incision. The foam bolster is engineered specifically to manifold -125 millimeters of mercury continuous negative pressure wound therapy evenly across the incision, while conforming to the incision site. For procedures that require customization, the 3M Prevena Plus Customizable dressing is available to provide greater flexibility for a wide variety of incision lengths and shapes, including linear, non-linear, and intersecting surgical incisions. This flexibility is achieved through a combination of additional features. The foam dressing can be cut for a wide variety of incision shapes and lengths. Hydrocolloid strips secure the dressing to the application site and create a continuous adhesive seal around the edges of the dressing to minimize the potential for leaks. The 3M VAC Drape covers the foam dressing and adheres to the skin, providing protection from external infectious materials. In addition, the 3M SensaT.R.A.C. Pad and Tubing utilizing 3M SensaT.R.A.C. technology connects directly to the 3M Prevena Plus 125 Therapy Unit via the 3M Prevena Plus connector without the need for a 3M Prevena Therapy VAC connector. SensaT.R.A.C. technology provides continual monitoring and adjustment of negative pressure at the incision site. The 3M Prevena Plus 150 milliliter canister allows for increased capacity of exudate storage. Finally, the AC adapter will allow charging of the battery and eliminates the need to replace batteries. To examine the biomechanical changes that occur under Prevena Therapy, computer simulations have been conducted. In the model, a closed incision in the skin can have uneven distribution of lateral tension around the suture line, forming subcutaneous incisional spaces that may permit fluid accumulation. This may compromise the integrity of the incision. When Prevena Therapy was applied in these computer simulations, there was about 50% reduction of lateral tension in the superficial suture line and an elimination of the incisional gap that helped maintain apposition of the incisional forces. The model also shows the stress distribution in the layers of the skin, which appears similar to normal uninjured tissue. The Prevena Incision Management System is an innovative therapy that covers and protects surgical incisions, holds incision edges together, and removes fluid and infectious material. Prevena Therapy has the most published clinical evidence than any negative pressure incision management system currently on the market, including 200 peer-reviewed articles and 30 randomized controlled trials. 3M Prevena Therapy.

    3M Prevena Therapy Skin Cube Cross Section from MOA video

    The 3M™ Prevena™ Incision Management System is intended to manage the environment of surgical incisions and surrounding intact skin in patients at risk for developing post-operative complications, such as infection, by maintaining a closed environment via the application of negative pressure therapy to the incision.

    It is indicated by FDA to help reduce superficial surgical site infections in patients at high-risk for post-operative complications in Class I and Class II wounds.*

    Prevena Therapy Mechanism of Action flyer (PDF, 300.31 KB)

    Prevena Therapy portfolio brochure (PDF, 2.14 MB)

    Prevena Therapy Mechanism of Action video

    *The effectiveness of Prevena Therapy in reducing the incidence of SSIs and seroma in all surgical procedures and populations has not been demonstrated. See full indications for use and limitations at myKCI.com.

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Proactive Risk Management (PRM) with Prevena Therapy

  • brochure thumbnail of clinicians using Prevena Therapy on a patient's abdomen

    PRM with Prevena Therapy provides healthcare professionals with an evidence-based, standardized approach that helps to advance the standard of care for closed incision negative pressure therapy (ciNPT). This intuitive, actionable model is grounded in level 1, 2 and 3 clinical evidence to help support you through procedural and patient risk stratification.

    Learn about PRM with Prevena Therapy

    Download 3M ciNPT Clinical Compendium (PDF, 5.58 MB)

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  • Prevena Therapy for Patients

    This helpful website explains the 3M™ Prevena™ Incision management system, as well as what to expect while a patient is using Prevena Therapy. Patients can find instructions, information on caring for the system, as well as frequently asked questions.

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    Download Patient Discharge Brochure (PDF, 2.06 MB)

  • VuMedi

    Find Prevena Therapy information on VuMedi, an online video education platform dedicated to delivering comprehensive healthcare professional education from leading institutions and practitioners.

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  • Negative Pressure Therapy (NPT) product page

    View product details and resources for 3M NPT kits, dressings, devices and accessories.

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  • 3M™ Prevena Restor™ Therapy product page

    See how Prevena Restor Therapy can help elevate your patients' postoperative outcomes by helping protect the surgical site and optimizing the healing environment.

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Events Calendar

View a comprehensive list of conferences we will be attending and information about upcoming medical education events.

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Testimonial videos

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Application videos

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Prevena Therapy Unit Recycling Program

3M has partnered with Sharps® Compliance, Inc. for the safe and environmentally friendly disposal of your 3M single-patient use, negative pressure therapy units, at no cost to you.

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Contact a representative

Contact a 3M representative for information or to request a demonstration.

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3M™ Prevena™ 125 and 3M™ Prevena™ Plus 125 Therapy Units manage the environment of closed surgical incisions and remove fluid away from the surgical incision via the application of -125mmHg continuous negative pressure. When used with legally marketed compatible dressings, Prevena 125 and Prevena Plus 125 Therapy Units are intended to aid in reducing the incidence of seroma and, in patients at risk for post-operative infections, aid in reducing the incidence of superficial surgical site infection in Class I and II wounds.

The effectiveness of Prevena Therapy in reducing the incidence of SSIs and seroma in all surgical procedures and populations has not been demonstrated. See full indications for use and limitations at myKCI.com.

NOTE: Applicable therapy units include Prevena™ 125 and Prevena™ Plus 125 Therapy Unit 7 Day.

The indication statement does not apply to the Prevena Plus 125 Therapy Unit (14-day) that comes with the 3M™ Prevena Restor™ System Kits (see Prevena Restor indications for use).

The 3M™ Prevena Restor™ Incision Management System is intended to manage the environment of surgical incisions that continue to drain following sutured or stapled closure by maintaining a closed environment and removing exudate via the application of negative pressure wound therapy.

NOTE: Specific indications, limitations, contraindications, warnings, precautions and safety information exist for these products and therapies. Please consult a clinician and product instructions for use prior to application. Rx only.