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Advancing the standard of care in orthopedics

3M™ Prevena™ Therapy

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Helping improve orthopedic patient outcomes

The value of Prevena Therapy as a tool for helping to manage surgical incisions is well established. Recent data confirms the effectiveness of Prevena Therapy in helping to lower the incidence of seroma and superficial surgical site infections (SSIs), in patients at high risk for post-operative infections* for improved orthopedic patient outcomes.

*The effectiveness of Prevena Therapy in reducing the incidence of SSIs and seroma in all surgical procedures and populations has not been demonstrated. See full indications for use and limitations at myKCI.com.


New data so strong from the PROMISES Multicenter, Randomized Control Trial that the study was terminated

  • Image of therapy system with different dressing sizes

    New data from a randomized controlled trial with at-risk patients further supports that Prevena Therapy significantly reduces the risk of 90-day surgical site complications (SSCs) and readmissions, when compared with the current standard of care (SOC). In fact, the evidence supporting the efficacy of Prevena Therapy was so strong that the study was terminated before its planned completion¹.

    Download Summary

    Read Full Study


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Thank you for downloading the PROMISES evidence summary

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Delivering the educational resources that customers need

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    Medical Education

    3M offers multiple educational resources to help clinicians optimize treatment, including: clinical training, real-world case studies, surgical videos, clinician testimonials, product-specific best practices, product support materials and on demand clinical and technical support.

    View Medical Education

    View 3Mˢᴹ Health Care Academy

  • Image of a doctor and nurse looking at a  clipboard.
    Orthopedic Clinical Evidence

    The potential clinical benefits of Prevena Therapy for orthopedic cases are outlined in nearly 30 journal publications. Read the highlights from six high evidence-level articles in an easy-to-read PDF.

    Download Orthopedic Clinical Evidence (PDF, 745 KB)

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    Prevena Therapy Information for Patients

    Access educational resources that can help your patients understand Prevena Therapy. These resources will help them determine what to do once they are discharged, where to go for important questions and how to troubleshoot their system.

    Download Patient Discharge Brochure (PDF, 800 KB)

    Watch Patient Education Video


Closed Incision Negative Pressure Therapy

  • Image of dressing applied to knee with therapy unit next to the leg
    Prevena Therapy

    Prevena Therapy focuses on managing the environment of closed surgical incisions to help reduce the risk of surgical site complications, such as superficial SSIs in patients at high risk for post-operative infections*, helping physicians and facilities reduce the associated costs and burden that comes with them.

    In 2019 Prevena Therapy became the first and only medical device indicated by FDA to aid in reducing the incidence of seromas and reducing superficial surgical site infections in Class I and Class II wounds, in high-risk patients* .

  • Image of patient with dressing on the knee sitting on a bed being examined by a clinician
    3M™ Prevena Restor™ Therapy

    Prevena Restor Therapy was developed to allow clinicians to manage the environment of closed incisions and the surrounding soft tissue with expanded dressing coverage and increasing to 14 days of therapy (Dressing change required after 7 days).

    3M™ Prevena Restor™ Dressing delivers therapy to the incision and surrounding soft tissue envelope helping to optimize post-operative recovery. It is designed for expanded coverage to bolster, stabilize and help reduce edema to the post-operative surgical site.

  • *The effectiveness of Prevena Therapy in reducing the incidence of SSIs and seroma in all surgical procedures and populations has not been demonstrated. See full indications for use and limitation at myKCI.com.


Prevena Therapy Mechanism of Action Video

Watch a minute-long MOA animation covering how Prevena Therapy covers and protects, removes fluids and infectious materials, and assists in holding the edges of incisions together while reducing lateral stress².

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  • References

    1.  The Effectiveness of Closed Incision Negative Pressure Therapy versus Silver-Impregnated Dressings in Mitigating Surgical Site Complications in High-Risk Patients After Revision Knee Arthroplasty. Higuera-Rueda CA, Emara AK, Nieves-Malloure Y, Klika AK, Cooper HJ, Cross MB, Guild GN, Nam D, Nett MP, Scuderi GR, Cushner FD, Piuzzi NS, Silverman RP. J. Arthroplasty 2021; doi: 10.1016/j.arth.2021.02.076

    2.  Closed incision management with negative pressure would therapy (CIM): biomechanics. Robert Peyton Wilkes, Deepak V Kilpadi, Yabin Zhao, Richard Kazala, Amy McNulty. Surgical Innovations 2012; doi: 10.1177/155

    3M™ Prevena™ 125 and 3M™ Prevena Plus™ 125 Therapy Units manage the environment of closed surgical incisions and remove fluid away from the surgical incision via the application of -125mmHg continuous negative pressure. When used with legally marketed compatible dressings, Prevena 125 and Prevena Plus 125 Therapy Units are intended to aid in reducing the incidence of seroma; and in patients at high risk for post-operative infections, aid in reducing the incidence of superficial surgical site infection in Class I and Class II wounds.

    The 3M™ Prevena Restor™ Incision Management System is intended to manage the environment of surgical incisions that continue to drain following sutured or stapled closure by maintaining a closed environment and removing exudate via the application of negative pressure wound therapy.

    NOTE: Specific indications, limitations, contraindications, warnings, precautions and safety information exist for these products and therapies. Please consult a clinician and product instructions for use prior to application. Rx only.